Assessment of Left Ventricular Volumes and Strain and Assessment of Valvular Lesions Using Two- and Three-dimensional Echocardiography and Cardiac MRI, a Correlation Study
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
The purpose of the study is to compare the various 2D and 3D methods of valvular heart disease quantification (Doppler, PISA, VCA, volumetric method) and strain with cardiac magnetic resonance (CMR) measurements of left and right ventricular systolic function strain and myocardial fibrosis assessment.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: f
View:
• Age 18-90 years of age
• Suspected moderate or severe MR,AR or AS on the basis of prior known clinical history or clinical exam.
• Suspected CRT non-responder with an implanted MRI compatible CRT device and reduced ejection fraction
Locations
United States
Ohio
Cleveland Clinic
RECRUITING
Cleveland
Contact Information
Primary
Deborah Kwon, M. D.
kwond@ccf.org
216-444-8526
Time Frame
Start Date: 2019-08-23
Estimated Completion Date: 2026-06-30
Participants
Target number of participants: 200
Treatments
Mitral Valve Regurgitation
Patients with moderate or severe (3+ or 4+) mitral valve regurgitation on the basis of prior known clinical history or clinical exam.
Aortic Valve Regurgitation
Patients with moderate or severe (3+ or 4+) aortic valve regurgitation on the basis of prior known clinical history or clinical exam.
Aortic Stenosis
Patients with moderate or severe (3+ or 4+) aortic stenosis on the basis of prior known clinical history or clinical exam.
Patients referred for CRT Implantation
Patients who meet clinical guideline criteria for CRT implantation with EF \< 40%
Related Therapeutic Areas
Sponsors
Leads: The Cleveland Clinic