A Phase I/II Randomized Double-Blinded Standard of Care (Corticosteroid) Vs. Sterile Amniotic Fluid for Osteoarthritis

• Patients who are between the ages of 18-70 years

• A confirmed diagnosis of knee osteoarthritis based on clinical and radiographic findings consistent with Kellgren-Lawrence Stage 2-3 disease

• Patients who have failed conservative treatment (e.g. steroid, activity modification, therapy, etc.) within 3 months

• Unilateral or bilateral chronic knee joint pain \>4 months

• Patients who are able to ambulate (i.e. not wheelchair bound)

• Patient reported a typical pain of at least 4 out of 10 during the past week using VAS numeric pain scale (0-10)

• Patients who are of childbearing potential must agree to use adequate contraception for 90 days after study drug injection