Pilot Study Using Transcranial Electrostimulation (TESA-HB) Therapy for the Treatment of Depressive Symptoms Associated With Mild to Moderate Depressive Episodes

Status: Terminated
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This pilot study uses TESA-HB therapy for treatment of depressive symptoms associated with mild and moderate depression episodes. Primary objectives of this pilot study are to demonstrate the safety of TESA-HB Therapy, and to investigate the efficacy of TESA-HB Therapy for depressive symptoms.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: t
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• Between the ages of 18-65 years old on enrollment

• Assessed by Evaluator with mild to moderate depressive episode, based on the MDI Rating Scale (20-24 mild; 25-29 moderate).

• Have average MDI pain rating score of \> 20 or \<29 during baseline

• Assessed by Evaluator to have mild to moderate depressive episode, based on the HAM-D21 Rating Scale (8-13 = mild; 14-17 moderate).

• Assessed by Evaluator to have mild to moderate depressive episode based on ICD-10 Diagnostic Guidelines 1,2

• Willing and able to visit 2 weeks ( 5 times per week) as a clinic outpatient to participate in this clinical investigation

• Willing and able to return to the clinic for evaluation during the follow up period - 2 weeks, 1 month (4 wks), 2 months (8 wks), and 3 months (12wks) following the completion of TESA-HB Therapy

• Willing to be monitored, fill out daily medication logs, and appear for all physician visits for baseline, treatment and follow-up period

• English speaking and able to understand and approve the consent form, and understand and provide answers on the Depression and Anxiety assessment form and the Psychological General Well-Being Index (PGWB-S) questionnaires

Locations
United States
Pennsylvania
Holy Redeemer Health Care at Bensalem, 3300 Tillman Drive
Bensalem
Time Frame
Start Date: 2017-09-26
Completion Date: 2019-01-31
Participants
Target number of participants: 12
Treatments
Experimental: Treatment Arm A
TESA-HB Device, Mode 3 (15mA). Treatment arm involves two 5-day treatment cycles over a 2-week period, with 2 days off between each of the 5-day cycles. The treatment period will as for two full weeks.
Sponsors
Leads: Annecto LLC
Collaborators: Holy Redeemer Hospital

This content was sourced from clinicaltrials.gov

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