Automatic Medication Increase Protocol in the Treatment of Elevated Blood Pressure

Status: Terminated
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Phase 1/Phase 2
SUMMARY

High blood pressure leads to heart attacks and strokes which can be prevented by blood pressure-lowering medication. However, the current office-based prescription of one pill and one dose at a time is ineffective. the investigators want to pilot-test a more effective patient-centered treatment approach, where patients will receive a prescription with gradual but automatic weekly increases of dose and number of pills. Patients will measure their blood pressure with an iPhone compatible cuff, which transmits readings to the doctor or pharmacist, who will stop escalation when the desired blood pressure level is reached. The investigators hypothesize that the intervention will decrease the time to control blood pressure and increase the overall rate of blood pressure control. Therefore, this new treatment model could prevent heart attacks and strokes, and reduce healthcare costs.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 55
Healthy Volunteers: f
View:

• 18 to 55 years old

• office BP of ≥160 mmHg systolic and ≥100 mmHg diastolic (treated or untreated) AND \<180 mmHg systolic.

Locations
United States
California
Cedars-Sinai Medical Center
Los Angeles
Time Frame
Start Date: 2013-11
Completion Date: 2015-12
Participants
Target number of participants: 3
Treatments
Experimental: default intensification arm (all)
all subjects will receive blister packs with weekly increasing blood pressure medications. There is no control arm for this study
Authors
Ronald Victor, Florian Rader
Related Therapeutic Areas
Sponsors
Leads: Cedars-Sinai Medical Center
Collaborators: University of California, Los Angeles

This content was sourced from clinicaltrials.gov

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