CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain )

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this study is to determine if rapid outpatient evaluation vs hospitalization management is the best strategy (based on patient-centered measures and safe, equitable, and efficient resource use) for evaluating patients with acute chest pain who are at moderate risk for acute coronary syndrome (ACS). Patients will be randomized in the Emergency Department to either an outpatient evaluation (CARE-CP) or hospitalization evaluation for their symptoms.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Healthy Volunteers: f
View:

• Age ≥21 years old

• Chest pain or Symptoms of acute coronary syndrome (ACS)

• Moderate risk of ACS (all of the below)

• Hear Score 4-6

• Non-Ischemic electrocardiogram (ECG)

• Two Troponin measures \< Sex-Specific Upper Reference Limit

‣ Women \<15 pg/ml

⁃ Men \<20 pg/ml

• No prior coronary artery disease (CAD)

‣ No Prior Myocardial Infarction (MI)

⁃ No Prior Coronary Revascularization Procedures

⁃ No Patients with ≥ 70% Obstructive Coronary Disease

Locations
United States
Michigan
Henry Ford Hospital
RECRUITING
Detroit
North Carolina
Carolinas Medical Center
RECRUITING
Charlotte
Wake Forest University Health Sciences
RECRUITING
Winston-salem
Contact Information
Primary
Lauren Koehler
lekoehle@wakehealth.edu
336-716-4646
Backup
Lauren Victory
lvictory@wakehealth.edu
336-716-7260
Time Frame
Start Date: 2023-10-02
Estimated Completion Date: 2026-10
Participants
Target number of participants: 502
Treatments
Other: Outpatient Evaluation
Patients randomized to this arm are discharged and receive outpatient evaluation, or cardiovascular ambulatory rapid evaluation (CARE), focused on medical management for cardiovascular risk factors (e.g. hypertension) within 72 hours of Emergency Department discharge.
Other: Hospitalization Evaluation
Patients randomized to this arm receive evaluation for their symptoms in a hospital ward, observation unit, or emergency department boarding.
Related Therapeutic Areas
Sponsors
Collaborators: Agency for Healthcare Research and Quality (AHRQ)
Leads: Wake Forest University Health Sciences

This content was sourced from clinicaltrials.gov

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