The Effects of Dexmedetomidine on Myocardial Repolarization in Children
Dexmedetomidine is a sedative drug that is commonly used to improve calmness and reduce pain in children waking up after surgery. Some of the side effects of dexmedetomidine, such as a potential change in how the heart muscles contract and changes in blood sugar and potassium levels, are poorly understood. The current study aims to examine these changes directly in healthy children undergoing elective surgery by measuring the heart beats (with an electrocardiogram) and blood sugar and potassium at specific times before and after dexmedetomidine is given. The investigators aim to establish a better understanding of this drug's safety profile.
• ASA Physical Status I-II
• Age 3 to 10yrs
• Elective surgical procedure requiring general anesthesia
• Use of dexmedetomidine acceptable to the staff anesthesiologist
• Un-premedicated
• Ability to read and understand English (parent/legal guardian(s) and child)