Mechanisms of Airway Protection Dysfunction in Parkinson's Disease
Status: Completed
Location: See location...
Intervention Type: Procedure, Drug, Other, Device
Study Type: Observational
SUMMARY
This study will collect data on various aspects of airway sensation and function, and determine how it relates to the development of swallowing and cough dysfunction in Parkinson's disease. Participants will be followed over a 3-year period, with once-per-year visits to collect the data.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 45
Maximum Age: 85
View:
• Between the ages of 45 and 85 years
• Diagnosis of PD, Hoehn and Yahr stages I - IV, by a fellowship trained neurologist arriving at the diagnosis of PD by applying strict UK brain bank criteria (PD participants only)
Locations
United States
Florida
University of Florida Center for Movement Disorders and Neurorestoration
Gainesville
Time Frame
Start Date: 2017-12-12
Completion Date: 2023-09-29
Participants
Target number of participants: 119
Treatments
Healthy controls
Men and women between the ages of 45 and 85 years without Parkinson's disease, or any history of neurologic disorder/disease, head or neck cancer, or chronic respiratory illness.
Parkinson's disease
Men and women between the ages of 45 and 85 years with Parkinson's disease, and without any history of neurologic disorder/disease, head or neck cancer, or chronic respiratory illness.
Authors
Paul W Davenport, Michael S Okun
Related Therapeutic Areas
Sponsors
Leads: University of Florida
Collaborators: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)