On-X Heart Valve - 17mm Aortic and 23mm Mitral

Status: Terminated
Location: See all (10) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study examines the hemodynamic and hemolytic properties of two additional smaller size valves to the On-X line of valves already approved by FDA.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Patients of any age; unless waived by local IRB assent of the patient and in all cases consent of parent or legally authorized representative is required if a patient is under the age of majority and not legally emancipated.

• Patients who are sufficiently ill to warrant replacement of their diseased natural or prosthetic valve, based on standard cardiovascular diagnostic workups.

• Patients who are in sufficient satisfactory condition, based on the physical exam and investigator's experience, to be an average or better operative risk, (i.e., likely to survive one year postoperatively).

• Patients who require an isolated aortic valve replacement size 17 mm or isolated mitral valve replacement size 23mm.

• Patients who are geographically stable and willing to return to the implanting center for follow-up visits.

• Patients or legally authorized representatives who are adequately informed of their participation in the clinical study and what will be required of them in order to comply with the protocol.

• Patients requiring concomitant cardiovascular surgery, such as coronary bypass may be included in the study.

Locations
United States
Arkansas
Arkansas Children's Hospital
Little Rock
Maine
Maine Medical Center
Portland
Nevada
Children's Heart Center Nevada
Las Vegas
Ohio
Cincinnati Children's Medical Center
Cincinnati
Oklahoma
University of Oklahoma/Children's Hospital
Oklahoma City
Virginia
University of Virginia
Charlottesville
Washington
Mary Bridge Children's - Tacoma General Hospital
Tacoma
Other Locations
Puerto Rico
Mayaguez Medical Center
Mayaguez
Spain
Hospital Clinico Provincial
Barcelona
University Hospital Salamanca
Salamanca
Time Frame
Start Date: 2011-11-18
Completion Date: 2018-12-07
Participants
Target number of participants: 20
Treatments
Experimental: 17mm On-X Aortic Heart Valve
Patients receiving the 17mm On-X aortic heart valve as a replacement for diseased native or prosthetic aortic heart valve.
Experimental: 23mm On-X Mitral Heart Valve
Patients receiving the 23mm On-X mitral heart valve as a replacement for diseased native or prosthetic mitral heart valve.~Enrollment into the 23mm On-X mitral arm has been terminated.
Sponsors
Leads: On-X Life Technologies, Inc.

This content was sourced from clinicaltrials.gov