The Impact of Cytochrome P450 Abnormalities in Patients With Delirium. A Pilot Study.
Objectives: 1. To examine whether patients with delirium have higher prevalence of cytochrome-P450 abnormalities compared to patients without delirium. 2. To examine whether the severity of delirium is related to a specific cytochrome P450 genotype. 3. To examine the persistence of delirium at 6-8 weeks stratified by presence of cytochrome p450 abnormalities 4. To examine whether delirium persistence is impacted by types of medications administered during their hospital stay.
• Patients age 18 and older admitted to the ALGH (Advocate Lutheran General Hospital) rehabilitation unit
• One or more of the Following Principle Diagnosis:
• Principle stroke diagnosis Principle Cardiac-Post cardiac surgery Principle Spinal surgery
• Non-English speakers are not anticipated. However, there is an available interpreter services already on the unit and this interpreter's services will be utilized. https://www.languageline.com/ However, we will utilize that AHC IRB approved short forms if a potential subject presents itself.