Evaluating Treatment Response in Laryngo-Pharyngeal Reflux

Status: Withdrawn
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Although laryno-pharyngeal reflux (LPR) and gastroesophageal reflux disease (GERD) differ in symptoms and treatment, they are diagnosed by the same standard 24-hour pH monitoring system which measures liquid reflux in the esophagus. The investigators are evaluating a new 24-hour pharyngeal pH monitoring system by Restech which can measure acid exposure in the airway and can be used specifically for LPR diagnosis. The purpose of this study is to determine whether the Restech device is more effective than standard pH monitoring in predicting the response to proton pump inhibitor (PPI) acid suppression therapy using Dexlansoprazole in patients with symptoms and/or manifestations of LPR.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age 18 years old or above

• Have a clinical diagnosis of LPR

• Able and willing to provide consent

Locations
United States
Washington
University of Washington
Seattle
Time Frame
Start Date: 2011-05
Completion Date: 2012-04
Sponsors
Collaborators: Takeda Pharmaceuticals North America, Inc.
Leads: University of Washington

This content was sourced from clinicaltrials.gov