Evaluating the Role of Pharyngeal High Resolution Manometry and Impedance (pHRMi) in the Longitudinal Evaluation of Swallow Function in Head and Neck Cancer Patients
Status: Withdrawn
Location: See all (2) locations...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Examining if the use of serial pHRMi to identify biomechanical changes in the swallow function of HNC patients treated with radiotherapy.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 100
Healthy Volunteers: f
View:
• Previously untreated head and neck cancer of any histology receiving radiation with curative oncologic intent regardless of the treatment modality.
‣ The radiation can be with or without prior surgery as part of the untreated HNC treatment plan.
⁃ The radiation can include concurrent chemotherapy or without.
• Capable of providing informed consent.
Locations
United States
Maryland
SKCCC at Johns Hopkins (East Baltimore Campus)
Baltimore
Suburban Hospital
Bethesda
Time Frame
Start Date: 2023-12
Completion Date: 2030-12
Treatments
Experimental: pHRMi in evaluation of swallowing function
Pharyngeal High Resolution Manometry and Impedance (pHRMi) evaluation of swallowing function at baseline, 3 months post radiation, then at 9 months
Authors
Ellen Stein, Ana Ponce Kiess, Christine Gourin, Carole Fakhry, William Ravich, Brandi Page, Alba Azola
Sponsors
Leads: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins