Aldosterone and Sodium Regulation in Postural Tachycardia Syndrome - Screening Protocol
The purpose of the study is to determine whether patients meet criteria for Postural Tachycardia Syndrome (or not) and have reduced blood volume (or not). Both of these are important screening elements to Aim 3 of a National Institutes of Health Grant. The purposes of Aim 3 are to determine 1. whether a high dietary sodium level appropriately expands plasma volume in Postural Orthostatic Tachycardia, 2. whether plasma renin activity and aldosterone are modified appropriately by changes in dietary sodium in Postural Tachycardia Syndrome and 3. whether patients with Postural Tachycardia Syndrome have improvements in their orthostatic tachycardia and symptoms as a result of a high dietary sodium level.
• Age between 18-50 years old
• Patients with suspected POTS and healthy volunteers
• Sedentary healthy subjects of similar age and gender than patients will also be recruited.
• Only female participants are eligible.
• Able and willing to provide informed consent