Safety and Efficacy of Serial Platelet-Rich Plasma Injections for Treatment of Vocal Fold Atrophy, Scar, and/or Sulcus Vocalis
Status: Completed
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study will investigate the safety and efficacy of four serial monthly vocal fold injections of platelet-rich plasma to treat dysphonia secondary to vocal fold atrophy, scar, and/or sulcus vocalis with glottal insufficiency
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Vocal fold atrophy, scar, and/or sulcus vocalis diagnosed on laryngeal video stroboscopy by a fellowship-trained laryngologist
• Patients with a pre-injection VHI-10 score of ≥ 10
• Willingness to follow study requirements and perform follow-up visits for up to 4 months following the procedure
• Ability to give informed consent
Locations
United States
California
University of Southern California
Los Angeles
Time Frame
Start Date: 2020-02-18
Completion Date: 2022-09-30
Participants
Target number of participants: 14
Treatments
Experimental: Serial PRP injections
This arm will receive experimental intervention of serial monthly platelet-rich plasma (PRP) injections to a unilateral vocal fold mucosa for a total of 4 injections.
Authors
Related Therapeutic Areas
Sponsors
Leads: University of Southern California