A Post-Market, Prospective, Multi-Center, Open-Label, Single Arm Clinical Evaluation of the Integra® Titan™ Modular Shoulder System Generation 2.5 for Primary Shoulder Joint Replacement

Status: Terminated
Location: See all (7) locations...
Intervention Type: Device
Study Type: Observational
SUMMARY

A post market, prospective, non-randomized, multi-center, open-label, clinical study using survivorship as the reference performance goal to study the safety and efficacy of the Titan Modular Shoulder System 2.5 when used for primary shoulder arthroplasty.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• For total shoulder arthroplasty, subjects must meet a, b, or c below:

‣ Severely painful and/or disabled joint resulting from osteoarthritis, traumatic arthritis or rheumatoid arthritis

⁃ Fracture-dislocations of the proximal humerus where the articular surface is severely comminuted, separated from its blood supply or where the surgeon's experience indicates that alternative methods of treatment are unsatisfactory

⁃ Other difficult clinical problems where shoulder arthrodesis or resection arthroplasty are not acceptable (e.g. -revision of a failed primary component)

• For shoulder hemiarthroplasty, subjects must meet any of the sub-criteria a - g below:

‣ Severely painful and/or disabled joint resulting from osteoarthritis, traumatic arthritis or rheumatoid arthritis

⁃ Fracture-dislocations of the proximal humerus where the articular surface is severely comminuted, separated from its blood supply or where the surgeon's experience indicates that alternative methods of treatment are unsatisfactory

⁃ Other difficult clinical problems where shoulder arthrodesis or resection arthroplasty are not acceptable (e.g. -revision of a failed primary component)

⁃ Ununited humeral head fractures

⁃ Avascular necrosis of the humeral head

⁃ Rotator cuff arthropathy

⁃ Deformity and/or limited motion

Locations
United States
Alabama
University of Alabama at Birmingham
Birmingham
Maryland
John Hopkins University
Columbia
Mississippi
Mississipi Bone and Joint Clinic
Starkville
New York
The Research Foundation for The State University of New York (SUNY)
Syracuse
Pennsylvania
Westphal Orthopaedics
Lancaster
Hospital of the University of Pennsylvania
Philadelphia
The Rothman Institute
Philadelphia
Time Frame
Start Date: 2017-08-01
Completion Date: 2023-03-10
Participants
Target number of participants: 58
Treatments
Integra Titan Modular Shoulder System 2.5
Related Therapeutic Areas
Sponsors
Leads: Smith & Nephew, Inc.

This content was sourced from clinicaltrials.gov