INSPIRE: A Multicenter Randomized Controlled Trial Integrating Health Informatics in a Scalable Stepped Care Self-Management Program for Survivors After Hematopoietic Cell Transplantation

Status: Completed
Location: See all (15) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

This phase III trial investigates health informatics and a self-management program for improving the health of cancer survivors after stem cell transplant. After transplant many survivors may feel stressed or may be unsure of what health care they need. A self-management program called INSPIRE, along with a personalized survivorship care plan may improve stress and health care for transplant survivors.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Received \>= 1 autologous or allogeneic (related or unrelated) HCT with curative intent at a participating transplant center for a hematologic malignancy

• Age 18 years of age or older at last transplant

• Survival 2-5 years after last HCT when first approached for enrollment

• In remission at time of study entry, may be receiving chemoprevention

• Internet and email access

• American and Canadian citizens, and/or those with mailing addresses in the United States (US)/Canada and/or temporarily residing anywhere outside the country (IE - military).

Locations
United States
Florida
Moffitt Cancer Center
Tampa
Illinois
Loyola University Medical Center
Maywood
Kansas
University of Kansas Cancer Center
Kansas City
Massachusetts
Massachusetts General Hospital Cancer Center
Boston
Michigan
Wayne State University/Karmanos Cancer Institute
Detroit
Minnesota
Center for International Blood and Marrow Transplant Research
Minneapolis
National Marrow Donor Program
Minneapolis
University of Minnesota/Masonic Cancer Center
Minneapolis
North Carolina
UNC Lineberger Comprehensive Cancer Center
Chapel Hill
New York
Roswell Park Cancer Institute
Buffalo
Ohio
Cleveland Clinic Foundation
Cleveland
Pennsylvania
University of Pennsylvania/Abramson Cancer Center
Philadelphia
Texas
Texas Oncology at Baylor Charles A Sammons Cancer Center
Dallas
Washington
Fred Hutch/University of Washington Cancer Consortium
Seattle
Wisconsin
Medical College of Wisconsin
Milwaukee
Time Frame
Start Date: 2020-10-29
Completion Date: 2023-12-31
Participants
Target number of participants: 546
Treatments
Experimental: Group I (INSPIRE, survivorship care plan)
Patients receive immediate access to the INSPIRE online program and personalized survivorship care plan.
Active_comparator: Group II (usual care)
Patients receive an online program linking to existing online survivor resources and a personalized survivorship care plan. Patients may receive access to the INSPIRE online program after 12 months.
Sponsors
Leads: Fred Hutchinson Cancer Center
Collaborators: National Cancer Institute (NCI)

This content was sourced from clinicaltrials.gov