The Impact of a Physical Activity Intervention in Older Patients Undergoing Adjuvant Chemotherapy for Colorectal Cancer: a Randomized, Controlled Trial
Status: Completed
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study will see if patient who undergo a physical activity intervention called Walk With Ease report experiencing less fatigue and a higher quality of life during chemotherapy for colorectal cancer than those who do not participate in this intervention.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: f
View:
• ≥ Age 60 years (no upper age limit)
• Diagnosis of stage II-III colon or rectal cancer planned for treatment with adjuvant chemotherapy scheduled as part of standard treatment
• Able to read English (required for CGA and other surveys administered)
• Approval from their treating physician to engage in moderate-intensity physical activity
• Patient-assessed ability to walk and engage in moderate physical activity
• Signed, IRB-approved written informed consent
Locations
United States
North Carolina
University of North Carolina at Chapel Hill
Chapel Hill
Time Frame
Start Date: 2014-06
Completion Date: 2019-09-18
Participants
Target number of participants: 36
Treatments
No_intervention: Control
This group will be receiving adjuvant chemotherapy for colorectal cancer. They will not participate in the Walk With Ease program. They will be followed up using standard of care.
Experimental: Intervention
This group will be receiving adjuvant chemotherapy for colorectal cancer. They will participate in the Walk With Ease (WWE) program during the course of their chemotherapy treatment. They will be requested to initiate the WWE starting on Day 1 of adjuvant chemotherapy. Participants are asked to walk at a safe and comfortable pace, increasing their minutes per day at a rate they can sustain, with the ultimate goal of 30 minutes/day for at least 5 days/week. They are asked to maintain a daily walking log that is provided to them, entering total minutes per day.~Participants will be asked to do the walking program independently (self-directed, not in a formal group with an instructor) throughout chemotherapy.
Authors
Kirsten A Nyrop, Hanna Sanoff, William Wood, Norman Sharpless, Trevor Jolly, Hyman B Muss, Grant R Williams
Related Therapeutic Areas
Sponsors
Collaborators: LCCC Geriatric Oncology Program
Leads: UNC Lineberger Comprehensive Cancer Center