Effect of soy isoflavone supplementation on menopausal quality of life.
Journal: Menopause (New York, N.Y.)
Published:
Abstract
Objective: The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women.
Methods: A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire.
Results: Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups.
Conclusions: Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women.
Authors
Paula Amato, Ronald Young, Francene Steinberg, Michael Murray, Richard Lewis, Margaret Cramer, Stephen Barnes, Kenneth Ellis, Roman Shypailo, Joe Fraley, Karen Konzelmann, Joan Fischer, Colette Lasalle, Elliot Smith, William Wong
Relevant Conditions