Broad Antimicrobial Resistance in a Case of Relapsing Babesiosis Successfully Treated With Tafenoquine.
Journal: Clinical Infectious Diseases : An Official Publication Of The Infectious Diseases Society Of America
Published:
Abstract
We describe a case of relapsing babesiosis in an immunocompromised patient. A point mutation in the Babesia microti 23S rRNA gene predicted resistance to azithromycin and clindamycin, whereas an amino acid change in the parasite cytochrome b predicted resistance to atovaquone. Following initiation of tafenoquine, symptoms and parasitemia resolved.
Authors
Ralph Rogers, Peter Krause, Ashlyn Norris, Michelle Ting, Ellen Nagami, Brian Cilley, Edouard Vannier
Relevant Conditions