ASSIST: Child Apraxia Speech Treatment

Who is this study for? Patients with childhood apraxia of speech
What treatments are being studied? ASSIST
Status: Active_not_recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Phase 1
SUMMARY

Childhood apraxia of speech (CAS) is a pediatric motor speech disorder that impairs the planning of movements needed for intelligible speech. Children with CAS often show little or slow progress in standard speech therapy. This research is a Phase 1 study that tests initial efficacy and optimal parameters of a theoretically based integral stimulation treatment called ASSIST (Apraxia of Speech Systematic Integral Stimulation Treatment). In three small randomized group design studies, children (N=20 per study) receive 16 hours of individual ASSIST. The three studies systematically investigate treatment intensity (2 vs. 4 weeks) and two critical aspects of target selection: complexity (simple vs. complex target) and lexicality (words vs. nonwords). Each study also systematically examines the effect of treatment on functional outcome measures, including parent ratings of intelligibility and communicative participation, and objective intelligibility measures obtained from unfamiliar listeners.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 4
Maximum Age: 9
Healthy Volunteers: t
View:

• Age between 4;0 and 9;11 (years;months) at enrollment, based on parent report.

• From homes where the primary language spoken is English, based on parent report.

• Verbal output (50+ words) and communicative intent, as determined by the clinician and parent report.

• Speech sound disorder, as determined by a score \<16th percentile on the Diagnostic Evaluation of Articulation and Phonology (DEAP) Articulation Assessment (Dodd et al., 2006) and/or the Goldman-Fristoe Test of Articulation (Goldman \& Fristoe, 2015).

• CAS as a primary speech diagnosis, based on the following criteria:

‣ An average rating \> 1 across three expert speech-language pathologists (SLPs), who will independently rate presence of CAS in children live or from video recordings of the assessment using a 3-point scale (0 = no CAS, 1 = possible CAS, 2 = CAS). These judgments will be based on perceptual speech features of CAS (inconsistent vowel and consonant errors, difficulties achieving and transitioning into articulatory configurations, abnormal prosody).

⁃ An Apraxia Score of 1 or 2 on a Maximum Performance protocol in which they sustain vowels and fricatives as long as possible and repeat syllables as fast as possible (Rvachew et al., 2005; Thoonen et al., 1999).

• Normal hearing based on parent report or passing a standard pure-tone audiometry hearing screening at 500, 1000, 2000, and 4000 Hz (ASHA, 1997).

• Typical nonverbal cognition as determined by a T-score within 1.5 standard deviation (SD) of the mean on nonverbal subtests of the Reynolds Intellectual Assessment Scales (Reynolds \& Kamphaus, 2003).

Locations
United States
Pennsylvania
Temple University
Philadelphia
Time Frame
Start Date: 2019-04-18
Completion Date: 2025-03-31
Participants
Target number of participants: 420
Treatments
Experimental: ASSIST
Study 1 and 2
No_intervention: Delayed Control
Study 1 and 2
Experimental: Massed ASSIST
Study 3
Experimental: Distributed ASSIST
Study 3
Related Therapeutic Areas
Sponsors
Leads: Temple University

This content was sourced from clinicaltrials.gov