Neuroplasticity in Auditory Aging_Auditory Temporal processing_Project 2

Status: Completed
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Millions of elderly adults in the USA have age related hearing loss (ARHL), a malady that affects half of adults 60-69 years, and the majority of older adults. This hearing loss not only impacts communication and functional ability, but also is strongly associated with cognitive decline and decreased quality of life. This project aims to develop effective strategies to compensate and reverse this process through a deeper understanding of plasticity and adaptive auditory function, and how to engage it and harness it to remedy ARHL.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: t
View:

• native speaker of English

• normal cognitive function as measured on Montreal Cognitive Assessment

• pass screening auditory brainstem response test to make sure they have recordable brainwaves to acoustic stimuli

• age and hearing sensitivity:

• young normal-hearing listeners, 18-35 years, hearing thresholds less than 25 decibels (dB) HL from 250 - 4000 Hz;

• older normal-hearing listeners, 65-85 years, hearing thresholds less than 25 dB HL, from 250-4000 Hz;

• older hearing-impaired listeners, 65-85 years, with mild-to-moderate, high frequency sensorineural hearing loss;

• high school diploma

Locations
United States
Maryland
University of Maryland
College Park
Time Frame
Start Date: 2018-02-21
Completion Date: 2024-05-31
Participants
Target number of participants: 405
Treatments
Experimental: Auditory training: temporal cues
Aim 1: Listeners will hear target acoustic stimuli that vary in a temporal (timing/duration) cue for 9, 1-hour training sessions and will receive correct-answer feedback.~Aim 2: Listeners will hear sentences that vary in speech rate for 6, 1-hour training sessions and will receive correct-answer feedback.
Active_comparator: Auditory training: non-temporal cues
Aim 1: Listeners will hear target acoustic stimuli that vary in either stimulus intensity or stimulus frequency during 9, 1-hour training sessions and will receive correct-answer feedback.~Aim 2: Listeners will hear speech in varying levels of noise during 6, 1-hour training sessions and will receive correct-answer feedback.
No_intervention: Passive control group (Aims 1 and 2)
Listeners will be evaluated on pre-training and post-training tests, but will receive no training at all.
Sponsors
Leads: University of Maryland, College Park
Collaborators: National Institute on Aging (NIA), National Institutes of Health (NIH)

This content was sourced from clinicaltrials.gov