Prognosis of Disseminated and Cerebral Toxoplasmosis Hospitalized in Intensive Care in the Era of PCR Diagnosis - Toxoplasmosis in ICU (TOXIC)
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Toxoplasmosis is a common infection whose clinical severity can sometimes justify admission to intensive care, especially in immunocompromised patients. This study should make it possible to evaluate the impact of different anti-infective treatment regimens and to highlight clinical-biological and prognostic differences depending on the type of underlying immunosuppression.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 100
Healthy Volunteers: f
View:
• Adult patient hospitalized in intensive care
• At least 1 organ failure (SOFA\> or =2)
• PCR toxoplasmosis on CSF, blood, BAL, or bone marrow positive within 7 days before or after admission to ICU
Locations
Other Locations
France
Cochin hospital
RECRUITING
Paris
Contact Information
Primary
Clara Vigneron, MD
clara.vigneron@aphp.fr
06 33 14 56 50
Backup
Romain Sonneville, MD, PhD
romain.sonneville@aphp.fr
01 40 25 61 39
Time Frame
Start Date: 2024-08-01
Estimated Completion Date: 2026-04-01
Participants
Target number of participants: 200
Related Therapeutic Areas
Sponsors
Leads: Assistance Publique - Hôpitaux de Paris