Proof-of-concept Study on the Efficacy of Light Therapy in the Prophylactic Treatment of Chronic Cluster Headache

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Cluster headache is a primary headache. The chronic form of the disease is often difficult to treat. It is now considered a chronobiological disease. This chronobiological character is based on clinical, biological and radiological arguments. This study focuses on the use of light therapy in cluster headache. Light therapy has already been used in the treatment of other chronobiological diseases, such as seasonal depression, but also recently in the therapy of other primary headaches (such as migraine). Its aim is to re-adjust chronobiological rhythms, and it therefore seems worth testing in the chronic form of cluster headache. Light therapy is delivered to the patient using a consumer electronics device.The main objective is to evaluate the prophylactic efficacy of light therapy in patients with chronic cluster headache.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Male or female, of 18 years years old or more;

• Diagnosis of chronic cluster headache according to ICHD-3 criteria;

• Presence of at least 1 attack/day during baseline period;

• Stability of prophylactic treatment for at least 1 month and commitment not to change it for the duration of the study;

• Patient affiliated to the French social security system.

• Patient who understands and speaks French correctly;

• Patient who has given free and informed written consent.

Locations
Other Locations
France
Hopital La Timone
RECRUITING
Marseille
Hôpital de Cimiez
NOT_YET_RECRUITING
Nice
Contact Information
Primary
Anne DONNET
anne.donnet@ap-hm.fr
+33491384345
Backup
Sophie Tardoski
sophie.tardoski@ap-hm.fr
0491381594 Ext. 33
Time Frame
Start Date: 2025-02-06
Estimated Completion Date: 2027-05-05
Participants
Target number of participants: 48
Treatments
Experimental: Experimental group (group 1)
Luminette® with active light emission in the 400 \< X \< 750 nm spectrum
Placebo_comparator: Control group (group 2)
Luminette ® with modified spectral parameters for wavelengths covered, with light emission in a spectrum of 560 \< X \< 650 nm assumed to have no therapeutic effect (placebo effect)
Related Therapeutic Areas
Sponsors
Leads: Assistance Publique Hopitaux De Marseille

This content was sourced from clinicaltrials.gov