A Randomized Controlled Trial on the Effect of Hydroxychloroquine in Mild Graves' Orbitopathy
Who is this study for? Patients with Graves' orbitopathy
What treatments are being studied? Hydroxychloroquine
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
This study is aimed to investigate the effect of hydroxychloroquine in patients with mild Graves' orbitopathy (GO).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• Mild GO according European Group on Graves' orbitopathy (EUGOGO) guidelines diagnosed by endocrinologist and ophthalmologist.
• No previous treatment of GO except for eyedrops
• Euthyroidism (normalized free T4 and TSH) for at least 2 months. If radioactive iodine is used for hyperthyroidism, euthyroidism needs to be achieved for at least 6 months.
Locations
Other Locations
Taiwan
National Taiwan University Hospital, Hsin-Chu branch
RECRUITING
Hsinchu
National Taiwan University Hospital
RECRUITING
Taipei
Contact Information
Primary
Shyang-Rong Shih
srshih@ntu.edu.tw
+886-2-23123456
Backup
Hung-Yuan Li
larsli@ntuh.gov.tw
+886-2-23123456
Time Frame
Start Date: 2022-03-21
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 108
Treatments
Experimental: Hydroxychloroquine
Hydroxychloroquine 200mg twice daily for 6 months.
No_intervention: Control
Observation and active surveillance.
Related Therapeutic Areas
Sponsors
Leads: National Taiwan University Hospital