Influence of Serum Sodium Levels on Bone Metabolism and Turnover in Hospitalized Patients - A Prospective Study (BONA-Trial)
Status: Completed
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
In this study, the possible role of serum sodium concentration and its changes on bone markers in hospitalized, hyponatremic patients is determined. Therefore, it is investigated whether in hospitalized, hyponatremic patients the level of carboxy-terminal collagen crosslinks (CTX) is modified by changes in plasma sodium concentration, independently from the aetiology of hyponatremia.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 99
Healthy Volunteers: f
View:
• Adult hospitalized patients with non-hypertonic hyponatremia: serum sodium \< 130 mmol/l, serum osmolality \< 300 milliosmol /kg
• age 18 to 99-year-old
• Informed consent as documented by signature
Locations
Other Locations
Switzerland
Endocrinology, Diabetes and Metabolism, University Hospital Basel
Basel
Time Frame
Start Date: 2020-02-13
Completion Date: 2025-02-24
Participants
Target number of participants: 52
Treatments
Hyponatremic patients
Patients hospitalized at the University Hospital of Basel and presenting with hyponatremia will be screened for the study
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Basel, Switzerland