Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease

Status: Active_not_recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Observational
SUMMARY

The aims of this study are to create a prospective data base to evaluate the long term outcomes of medical and surgical treatment of gastroesophageal reflux disease (GERD); to measure standard outcomes as well as patient derived outcomes such as general and disease specific quality of life (QOL) issues and patient satisfaction; to refine the parameters that may identify patients who will benefit from surgery for GERD; and to identify possible determinants of failure of both medical and surgical treatments of reflux.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients with reflux symptoms present for at least 6 months, caused by documented reflux. Reflux symptoms include:

‣ heartburn

⁃ acid regurgitation

⁃ waterbrash

⁃ non-cardiac chest pain

⁃ dyspepsia

• Reflux diagnosis either by endoscopy, upper gastrointestinal (GI), or 24 hour pH.

• Patients scheduled for surgical management of GERD and/or hiatal hernia

• Patients currently or commencing treatment with at least proton pump inhibitors or pro-motility agents.

Locations
United States
Pennsylvania
UPMC Department of Cardiothoracic Surgery
Pittsburgh
Time Frame
Start Date: 1999-04
Completion Date: 2050-12
Participants
Target number of participants: 2500
Sponsors
Leads: University of Pittsburgh

This content was sourced from clinicaltrials.gov