Percutaneous Cordotomy for Pain Palliation in Advanced Cancer
Status: Active_not_recruiting
Location: See location...
Intervention Type: Other, Procedure, Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This trial studies how well cordotomy works in reducing pain in patients with cancer that has spread to other places in the body (advanced). Cordotomy is performed on the spinal cord with a needle and guided by computed tomography scans and is designed to help reduce pain. This study is being done to learn if a cordotomy reduces pain in patients with unmanageable cancer pain.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Ability to provide informed consent
• Has undergone 3 palliative care evaluations
• Pain intensity \>= 4 on a 0-10 numerical scale
• Unilateral pain due to cancer below the shoulder level (arm, trunk, hip, leg)
Locations
United States
Texas
M D Anderson Cancer Center
Houston
Time Frame
Start Date: 2019-09-16
Completion Date: 2025-12-01
Participants
Target number of participants: 27
Treatments
Experimental: Group I (cordotomy)
Patients undergo a cordotomy over 1-2 hours.
Sham_comparator: Group II (morphine, fake cordotomy)
Patients receive morphine via injection into the spine and undergo a fake cordotomy over 1-2 hours.
Authors
Related Therapeutic Areas
Sponsors
Leads: M.D. Anderson Cancer Center
Collaborators: National Institute of Nursing Research (NINR), National Cancer Institute (NCI)