A Randomized Double-blind, Placebo-controlled, Multicenter Trial Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With Established Cardiovascular Disease
Who is this study for? Patients with Cardiovascular Disease and Lipoprotein
What treatments are being studied? TQJ230
Status: Active_not_recruiting
Location: See all (746) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
This is a pivotal phase 3 study designed to support an indication for the reduction of cardiovascular risk in patients with established CVD and elevated Lp(a)
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Lp(a) ≥ 70 mg/dL at the screening visit, measured at the Central laboratory
• Myocardial infarction: ≥ 3 months from screening and randomization to ≤ 10 years prior to the screening visit
• Ischemic stroke: ≥ 3 months from screening and randomization to ≤ 10 years prior to the screening visit
• Clinically significant symptomatic peripheral artery disease
Locations
United States
Alabama
SEC Clinical Research LLC
Andalusia
Novartis Investigative Site
Birmingham
Novartis Investigative Site
Huntsville
Novartis Investigative Site
Mobile
Arkansas
Novartis Investigative Site
Little Rock
Arizona
Novartis Investigative Site
Cottonwood
Mercy Gilbert Medical Center
Gilbert
Novartis Investigative Site
Sun City West
Novartis Investigative Site
Tucson
California
Cardiovascular Res Found
Beverly Hills
Novartis Investigative Site
Beverly Hills
Novartis Investigative Site
Covina
Novartis Investigative Site
Huntington Beach
Novartis Investigative Site
La Jolla
Novartis Investigative Site
Long Beach
Novartis Investigative Site
Los Angeles
Novartis Investigative Site
Los Angeles
Novartis Investigative Site
Northridge
Novartis Investigative Site
Orange
University of California San Diego
San Diego
Novartis Investigative Site
San Francisco
UCSF
San Francisco
Novartis Investigative Site
Santa Ana
Novartis Investigative Site
Stanford
Novartis Investigative Site
Stockton
Novartis Investigative Site
West Hills
Colorado
Novartis Investigative Site
Aurora
Connecticut
Novartis Investigative Site
Bridgeport
Novartis Investigative Site
Hartford
Novartis Investigative Site
Waterbury
Florida
Novartis Investigative Site
Boca Raton
Novartis Investigative Site
Bradenton
Novartis Investigative Site
Brandon
Novartis Investigative Site
Fort Lauderdale
East Coast Institute for Research
Jacksonville
Novartis Investigative Site
Jacksonville
Novartis Investigative Site
Jacksonville
Novartis Investigative Site
Miami
Novartis Investigative Site
Naples
Novartis Investigative Site
Port Charlotte
Novartis Investigative Site
Port Orange
Novartis Investigative Site
Saint Augustine
Novartis Investigative Site
Wellington
Georgia
Emory University
Atlanta
Novartis Investigative Site
Atlanta
Novartis Investigative Site
Atlanta
Novartis Investigative Site
Atlanta
Novartis Investigative Site
Dunwoody
Novartis Investigative Site
Thomasville
Iowa
Novartis Investigative Site
Iowa City
Illinois
Rush University Medical Center
Chicago
Novartis Investigative Site
Park Ridge
Indiana
Novartis Investigative Site
Indianapolis
Kansas
Novartis Investigative Site
Kansas City
Novartis Investigative Site
Topeka
Louisiana
Novartis Investigative Site
Alexandria
Novartis Investigative Site
Baton Rouge
Novartis Investigative Site
Bogalusa
Novartis Investigative Site
Bossier City
Novartis Investigative Site
Covington
Novartis Investigative Site
Eunice
Novartis Investigative Site
Hammond
Novartis Investigative Site
Houma
Horizon Research Grp
Lafayette
Novartis Investigative Site
Metairie
Novartis Investigative Site
New Orleans
Tulane Uni Health Sciences Center
New Orleans
Novartis Investigative Site
Opelousas
Grace Research Llc
Shreveport
Novartis Investigative Site
Shreveport
Novartis Investigative Site
Slidell
Novartis Investigative Site
Zachary
Massachusetts
Novartis Investigative Site
Boston
Novartis Investigative Site
Boston
Maryland
Novartis Investigative Site
Baltimore
Novartis Investigative Site
Baltimore
Novartis Investigative Site
Baltimore
Novartis Investigative Site
Columbia
Novartis Investigative Site
Fort Washington
Novartis Investigative Site
Rockville
Maine
Novartis Investigative Site
Scarborough
Michigan
Novartis Investigative Site
Detroit
Novartis Investigative Site
Detroit
Novartis Investigative Site
Flint
Genesys Regional Medical Center
Grand Blanc
Novartis Investigative Site
Grand Blanc
Novartis Investigative Site
Kalamazoo
Novartis Investigative Site
Petoskey
Novartis Investigative Site
Saginaw
Novartis Investigative Site
Wyoming
Minnesota
Saint Johns Hospital
Maplewood
Novartis Investigative Site
Minneapolis
Novartis Investigative Site
Minneapolis
Missouri
Mercy Hospital St Louis
Saint Louis
Mercy South
Saint Louis
Novartis Investigative Site
Saint Louis
Novartis Investigative Site
Saint Peters
Mississippi
Novartis Investigative Site
Belzoni
Novartis Investigative Site
Southaven
Novartis Investigative Site
Yazoo City
North Carolina
Novartis Investigative Site
Charlotte
Medication Management LLC
Greensboro
Novartis Investigative Site
Greensboro
Novartis Investigative Site
High Point
Accellacare US Inc
Raleigh
Novartis Investigative Site
Sanford
Novartis Investigative Site
Shelby
Novartis Investigative Site
Winston-salem
Wake Forest University Baptist Medical Center
Winston-salem
Nebraska
Novartis Investigative Site
Lincoln
Novartis Investigative Site
Omaha
New Hampshire
Novartis Investigative Site
Lebanon
New Jersey
Novartis Investigative Site
Ridgewood
Novartis Investigative Site
Summit
New York
Albany Medical College
Albany
Novartis Investigative Site
Manhasset
Lenox Hill Hospital
New York
Novartis Investigative Site
New York
Novartis Investigative Site
New York
Novartis Investigative Site
New York
Novartis Investigative Site
New York
Rochester Regional Health
Rochester
Strong Memorial Hospital
Rochester
Novartis Investigative Site
Southampton
Ohio
Akron Hospital Summa Health System
Akron
Novartis Investigative Site
Akron
Novartis Investigative Site
Canton
Novartis Investigative Site
Cincinnati
Novartis Investigative Site
Cincinnati
Novartis Investigative Site
Cincinnati
Novartis Investigative Site
Cleveland
Novartis Investigative Site
Columbus
Novartis Investigative Site
Marion
Oregon
Novartis Investigative Site
Portland
Pennsylvania
Novartis Investigative Site
Lancaster
Novartis Investigative Site
Philadelphia
Allegheny General Hospital
Pittsburgh
Novartis Investigative Site
Yardley
Rhode Island
Novartis Investigative Site
Providence
South Carolina
Novartis Investigative Site
Fort Mill
Novartis Investigative Site
Summerville
South Dakota
Novartis Investigative Site
Rapid City
Tennessee
Novartis Investigative Site
Germantown
Novartis Investigative Site
Jackson
Novartis Investigative Site
Nashville
Cardiovascular Res of Knoxville LLC
Powell
Novartis Investigative Site
Powell
Texas
Novartis Investigative Site
Dallas
Novartis Investigative Site
Dallas
Novartis Investigative Site
Dallas
UT Southwestern Medical Center
Dallas
Novartis Investigative Site
Houston
Novartis Investigative Site
Livingston
Grace Research
Marshall
Novartis Investigative Site
Temple
Novartis Investigative Site
Tomball
Utah
Novartis Investigative Site
Bountiful
Novartis Investigative Site
Murray
The University of Utah
Salt Lake City
Virginia
Novartis Investigative Site
Danville
Inova Fairfax Hospital
Falls Church
Novartis Investigative Site
Falls Church
Novartis Investigative Site
Manassas
Novartis Investigative Site
Norfolk
Novartis Investigative Site
Richmond
Washington
Novartis Investigative Site
Seattle
Novartis Investigative Site
Seattle
Novartis Investigative Site
Seattle
Univ of Washington Medical Center
Seattle
Wisconsin
Novartis Investigative Site
Milwaukee
West Virginia
West Virginia University Hospital
Morgantown
Other Locations
Argentina
Novartis Investigative Site
Caba
Novartis Investigative Site
Caba
Novartis Investigative Site
Caba
Novartis Investigative Site
Caba
Novartis Investigative Site
Caba
Novartis Investigative Site
Capital Federal
Novartis Investigative Site
Cordoba
Novartis Investigative Site
Cordoba
Novartis Investigative Site
Corrientes
Novartis Investigative Site
Mar Del Plata
Novartis Investigative Site
Ramos Mejia
Novartis Investigative Site
Rosario
Novartis Investigative Site
Rosario
Novartis Investigative Site
San Luis
Novartis Investigative Site
San Miguel De Tucuman
Novartis Investigative Site
Santa Fe
Novartis Investigative Site
Tucuman
Australia
Novartis Investigative Site
Camperdown
Novartis Investigative Site
Chemside
Novartis Investigative Site
Clayton
Novartis Investigative Site
Liverpool
Novartis Investigative Site
Perth
Novartis Investigative Site
Southport
Novartis Investigative Site
Woolloongabba
Austria
Novartis Investigative Site
Graz
Novartis Investigative Site
Innsbruck
Novartis Investigative Site
Linz
Novartis Investigative Site
Salzburg
Novartis Investigative Site
Wien
Novartis Investigative Site
Wien
Belgium
Novartis Investigative Site
Aalst
Novartis Investigative Site
Brugge
Novartis Investigative Site
Bruxelles
Novartis Investigative Site
Dendermonde
Novartis Investigative Site
Genk
Novartis Investigative Site
Huy
Novartis Investigative Site
Kortrijk
Novartis Investigative Site
Mechelen
Brazil
Novartis Investigative Site
Aracaju
Novartis Investigative Site
Belo Horizonte
Novartis Investigative Site
Belo Horizonte
Novartis Investigative Site
Blumenau
Novartis Investigative Site
Brasilia
Novartis Investigative Site
Campinas
Novartis Investigative Site
Campinas
Novartis Investigative Site
Canoas
Novartis Investigative Site
Curitiba
Novartis Investigative Site
Curitiba
Novartis Investigative Site
Goiania
Novartis Investigative Site
Juiz De Fora
Novartis Investigative Site
Maceio
Novartis Investigative Site
Porto Alegre
Novartis Investigative Site
Porto Alegre
Novartis Investigative Site
Ribeirao Preto
Novartis Investigative Site
Rio De Janeiro
Novartis Investigative Site
Salvador
Novartis Investigative Site
Santo Andre
Novartis Investigative Site
Santo Andre
Novartis Investigative Site
Sao Jose Do Rio Preto
Novartis Investigative Site
Sao Jose Do Rio Preto
Novartis Investigative Site
Sao Paulo
Novartis Investigative Site
Sao Paulo
Novartis Investigative Site
Sao Paulo
Novartis Investigative Site
Sao Paulo
Novartis Investigative Site
Sao Paulo
Novartis Investigative Site
Sao Paulo
Novartis Investigative Site
Sao Paulo
Novartis Investigative Site
Uberlandia
Novartis Investigative Site
Vitoria
Bulgaria
Novartis Investigative Site
Blagoevgrad
Novartis Investigative Site
Burgas
Novartis Investigative Site
Pernik
Novartis Investigative Site
Pleven
Novartis Investigative Site
Plovdiv
Novartis Investigative Site
Ruse
Novartis Investigative Site
Sofia
Novartis Investigative Site
Sofia
Canada
Novartis Investigative Site
Levis
Novartis Investigative Site
Montreal
Novartis Investigative Site
Montreal
Novartis Investigative Site
Montreal
Novartis Investigative Site
Montreal
Novartis Investigative Site
Oakville
Novartis Investigative Site
Quebec
Novartis Investigative Site
Quebec
Novartis Investigative Site
Quebec
Novartis Investigative Site
Sainte Foy
Novartis Investigative Site
Terrebonne
Novartis Investigative Site
Toronto
Novartis Investigative Site
Vancouver
Novartis Investigative Site
Vancouver
Novartis Investigative Site
Victoria
Novartis Investigative Site
Victoria
Chile
Novartis Investigative Site
Santiago
Novartis Investigative Site
Santiago
Novartis Investigative Site
Santiago
Novartis Investigative Site
Santiago
Novartis Investigative Site
Santiago
Novartis Investigative Site
Santiago
China
Novartis Investigative Site
Baotou
Novartis Investigative Site
Beijing
Novartis Investigative Site
Beijing
Novartis Investigative Site
Beijing
Novartis Investigative Site
Beijing
Novartis Investigative Site
Chang Chun
Novartis Investigative Site
Changsha
Novartis Investigative Site
Changsha
Novartis Investigative Site
Changsha
Novartis Investigative Site
Chengdu
Novartis Investigative Site
Dalian
Novartis Investigative Site
Foshan
Novartis Investigative Site
Guangzhou
Novartis Investigative Site
Hangzhou
Novartis Investigative Site
Hangzhou
Novartis Investigative Site
Harbin
Novartis Investigative Site
Jinan
Novartis Investigative Site
Lanzhou
Novartis Investigative Site
Nanjing
Novartis Investigative Site
Nanjing
Novartis Investigative Site
Nanjing
Novartis Investigative Site
Shanghai
Novartis Investigative Site
Shanghai
Novartis Investigative Site
Shanghai
Novartis Investigative Site
Shenyang
Novartis Investigative Site
Shenyang
Novartis Investigative Site
Suzhou
Novartis Investigative Site
Tianjin
Novartis Investigative Site
Tianjin
Novartis Investigative Site
Tianjin
Novartis Investigative Site
Wenzhou
Novartis Investigative Site
Wuhan
Novartis Investigative Site
Wulumuqi
Novartis Investigative Site
Xiamen
Novartis Investigative Site
Xian
Novartis Investigative Site
Xuzhou
Colombia
Novartis Investigative Site
Barranquilla
Novartis Investigative Site
Bogota
Novartis Investigative Site
Bucaramanga
Novartis Investigative Site
Cali
Novartis Investigative Site
Cali
Novartis Investigative Site
Medellin
Novartis Investigative Site
Medellin
Novartis Investigative Site
San Gil
Denmark
Novartis Investigative Site
Aalborg
Novartis Investigative Site
Arhus N
Novartis Investigative Site
Esbjerg
Novartis Investigative Site
Glostrup
Novartis Investigative Site
Herlev
Novartis Investigative Site
Roskilde
Novartis Investigative Site
Viborg
France
Novartis Investigative Site
Bron
Novartis Investigative Site
Chambray Les Tours
Novartis Investigative Site
Compiegne
Novartis Investigative Site
Grenoble
Novartis Investigative Site
Le Coudray
Novartis Investigative Site
Lille
Novartis Investigative Site
Nantes Cedex 1
Novartis Investigative Site
Paris
Novartis Investigative Site
Paris
Novartis Investigative Site
Paris
Novartis Investigative Site
Toulouse 4
Novartis Investigative Site
Tourcoing
Novartis Investigative Site
Valenciennes
Germany
Novartis Investigative Site
Aachen
Novartis Investigative Site
Bad Homburg
Novartis Investigative Site
Bad Krozingen
Novartis Investigative Site
Bad Oeynhausen
Novartis Investigative Site
Bamberg
Novartis Investigative Site
Berlin
Novartis Investigative Site
Berlin
Novartis Investigative Site
Berlin
Novartis Investigative Site
Berlin
Novartis Investigative Site
Berlin
Novartis Investigative Site
Berlin
Novartis Investigative Site
Bielefeld
Novartis Investigative Site
Chemnitz
Novartis Investigative Site
Chemnitz
Novartis Investigative Site
Dessau-roßlau
Novartis Investigative Site
Dortmund
Novartis Investigative Site
Dresden
Novartis Investigative Site
Dresden
Novartis Investigative Site
Dresden
Novartis Investigative Site
Dresden
Novartis Investigative Site
Essen
Novartis Investigative Site
Essen
Novartis Investigative Site
Essen
Novartis Investigative Site
Frankfurt
Novartis Investigative Site
Frankfurt
Novartis Investigative Site
Gelnhausen
Novartis Investigative Site
Hamburg
Novartis Investigative Site
Hamburg
Novartis Investigative Site
Hannover
Novartis Investigative Site
Jena
Novartis Investigative Site
Kassel
Novartis Investigative Site
Koeln
Novartis Investigative Site
Koeln-nippes
Novartis Investigative Site
Kuenzing
Novartis Investigative Site
Leipzig
Novartis Investigative Site
Leipzig
Novartis Investigative Site
Loehne
Novartis Investigative Site
Lueneburg
Novartis Investigative Site
Lutherstadt Wittenberg
Novartis Investigative Site
Magdeburg
Novartis Investigative Site
Mannheim
Novartis Investigative Site
Mannheim
Novartis Investigative Site
Meissen
Novartis Investigative Site
Muehldorf
Novartis Investigative Site
Muenchen
Novartis Investigative Site
Muenchen
Novartis Investigative Site
Muenster
Novartis Investigative Site
Potsdam
Novartis Investigative Site
Ruedersdorf
Novartis Investigative Site
Saint Ingbert Oberwuerzbach
Novartis Investigative Site
Ulm
Novartis Investigative Site
Warendorf
Novartis Investigative Site
Weiden
Greece
Novartis Investigative Site
Athens
Novartis Investigative Site
Athens
Novartis Investigative Site
Athens
Novartis Investigative Site
Chalkida
Novartis Investigative Site
Ioannina
Novartis Investigative Site
Larissa
Novartis Investigative Site
Thessaloniki
Guatemala
Novartis Investigative Site
Guatemala
Novartis Investigative Site
Guatemala
Novartis Investigative Site
Guatemala
Novartis Investigative Site
Guatemala City
Novartis Investigative Site
Guatemala City
Hong Kong Special Administrative Region
Novartis Investigative Site
Hong Kong
Novartis Investigative Site
Shatin
Hungary
Novartis Investigative Site
Baja
Novartis Investigative Site
Budapest
Novartis Investigative Site
Budapest
Novartis Investigative Site
Budapest
Novartis Investigative Site
Budapest
Novartis Investigative Site
Debrecen
Novartis Investigative Site
Kistarcsa
Novartis Investigative Site
Mako
Novartis Investigative Site
Miskolc
Novartis Investigative Site
Nyiregyhaza
Novartis Investigative Site
Pecs
Novartis Investigative Site
Szeged
Novartis Investigative Site
Szekesfehervar
Iceland
Novartis Investigative Site
Kopavogur
Novartis Investigative Site
Reykjavik
India
Novartis Investigative Site
Ahmedabad
Novartis Investigative Site
Ahmedabad
Novartis Investigative Site
Belgavi
Novartis Investigative Site
Bengaluru
Novartis Investigative Site
Bikaner
Novartis Investigative Site
Chennai
Novartis Investigative Site
Coimbatore
Novartis Investigative Site
Coimbatore
Novartis Investigative Site
Dehradun
Novartis Investigative Site
Ghaziabad
Novartis Investigative Site
Guntur
Novartis Investigative Site
Hyderabad
Novartis Investigative Site
Hyderabad
Novartis Investigative Site
Hyderabad
Novartis Investigative Site
Kochi
Novartis Investigative Site
Kochi
Novartis Investigative Site
Kochi
Novartis Investigative Site
Kozhikode
Novartis Investigative Site
Lucknow
Novartis Investigative Site
Mangalore
Novartis Investigative Site
Manipal
Novartis Investigative Site
Mumbai
Novartis Investigative Site
Nagpur
Novartis Investigative Site
Nagpur
Novartis Investigative Site
Nagpur
Novartis Investigative Site
Nagpur
Novartis Investigative Site
Nashik
Novartis Investigative Site
New Delhi
Novartis Investigative Site
New Delhi
Novartis Investigative Site
New Delhi
Novartis Investigative Site
Pune
Novartis Investigative Site
Pune
Novartis Investigative Site
Pune
Novartis Investigative Site
Secunderabad
Novartis Investigative Site
Vadodara
Novartis Investigative Site
Varanasi
Israel
Novartis Investigative Site
Beer Sheva
Novartis Investigative Site
Haifa
Novartis Investigative Site
Haifa
Novartis Investigative Site
Holon
Novartis Investigative Site
Jerusalem
Novartis Investigative Site
Petach Tikva
Novartis Investigative Site
Ramat Gan
Italy
Novartis Investigative Site
Ancona
Novartis Investigative Site
Bergamo
Novartis Investigative Site
Bologna
Novartis Investigative Site
Brescia
Novartis Investigative Site
Cona
Novartis Investigative Site
Firenze
Novartis Investigative Site
Milano
Novartis Investigative Site
Milano
Novartis Investigative Site
Milano
Novartis Investigative Site
Milano
Novartis Investigative Site
Napoli
Novartis Investigative Site
Palermo
Novartis Investigative Site
Perugia
Novartis Investigative Site
Pisa
Novartis Investigative Site
Pozzilli
Novartis Investigative Site
Roma
Novartis Investigative Site
Roma
Novartis Investigative Site
Rozzano
Novartis Investigative Site
Salerno
Novartis Investigative Site
Varese
Japan
Novartis Investigative Site
Asahi
Novartis Investigative Site
Bunkyo Ku
Novartis Investigative Site
Chuo Ku
Novartis Investigative Site
Chuo-ku
Novartis Investigative Site
Fukuoka City
Novartis Investigative Site
Funabashi
Novartis Investigative Site
Hachioji
Novartis Investigative Site
Hirosaki
Novartis Investigative Site
Itabashi-ku
Novartis Investigative Site
Kahoku-gun
Novartis Investigative Site
Kanazawa
Novartis Investigative Site
Kawaguchi-city
Novartis Investigative Site
Kawasaki
Novartis Investigative Site
Kitakyushu-city
Novartis Investigative Site
Komatsu
Novartis Investigative Site
Kure-city
Novartis Investigative Site
Matsudo-city
Novartis Investigative Site
Miyhazaki-city
Novartis Investigative Site
Nagaoka
Novartis Investigative Site
Nagoya
Novartis Investigative Site
Ogaki-city
Novartis Investigative Site
Omihachiman
Novartis Investigative Site
Osaka
Novartis Investigative Site
Osaka City
Novartis Investigative Site
Ota-ku
Novartis Investigative Site
Sagamihara
Novartis Investigative Site
Sayama-city
Novartis Investigative Site
Sendai City
Novartis Investigative Site
Seto-city
Novartis Investigative Site
Shinagawa-ku
Novartis Investigative Site
Takamatsu City
Novartis Investigative Site
Toshima-ku
Novartis Investigative Site
Tsuchiura
Novartis Investigative Site
Yokohama
Novartis Investigative Site
Yokohama City
Mexico
Novartis Investigative Site
Aguascalientes
Novartis Investigative Site
Cuernavaca
Novartis Investigative Site
Culiacan Sinaloa
Novartis Investigative Site
Distrito Federal
Novartis Investigative Site
San Luis Potosi
Netherlands
Novartis Investigative Site
Alkmaar
Novartis Investigative Site
Amersfoort
Novartis Investigative Site
Amsterdam
Novartis Investigative Site
Amsterdam
Novartis Investigative Site
Apeldoorn
Novartis Investigative Site
Arnhem
Novartis Investigative Site
Delft
Novartis Investigative Site
Den Haag
Novartis Investigative Site
Deventer
Novartis Investigative Site
Enschede
Novartis Investigative Site
Gouda
Novartis Investigative Site
Groningen
Novartis Investigative Site
Hardenberg
Novartis Investigative Site
Heemstede
Novartis Investigative Site
Heerlen
Novartis Investigative Site
Leiden
Novartis Investigative Site
Leiderdorp
Novartis Investigative Site
Nijmegen
Novartis Investigative Site
Nijmegen
Novartis Investigative Site
Sneek
Novartis Investigative Site
Tiel
Novartis Investigative Site
Tilburg
Novartis Investigative Site
Utrecht
Novartis Investigative Site
Venlo
Novartis Investigative Site
Zwolle
Norway
Novartis Investigative Site
Oslo
Novartis Investigative Site
Skedsmokorset
Peru
Novartis Investigative Site
San Miguel
Poland
Novartis Investigative Site
Bielsko-biala
Novartis Investigative Site
Chrzanow
Novartis Investigative Site
Gdansk
Novartis Investigative Site
Gdynia
Novartis Investigative Site
Kedzierzyn Kozle
Novartis Investigative Site
Krakow
Novartis Investigative Site
Krakow
Novartis Investigative Site
Lodz
Novartis Investigative Site
Lodz
Novartis Investigative Site
Poznan
Novartis Investigative Site
Sochaczew
Novartis Investigative Site
Tarnow
Portugal
Novartis Investigative Site
Coimbra
Novartis Investigative Site
Guimaraes
Novartis Investigative Site
Setubal
Puerto Rico
Novartis Investigative Site
Ponce
Republic of Korea
Novartis Investigative Site
Bundang Gu
Novartis Investigative Site
Busan
Novartis Investigative Site
Daegu
Novartis Investigative Site
Gwangju
Novartis Investigative Site
Incheon
Novartis Investigative Site
Seoul
Novartis Investigative Site
Seoul
Novartis Investigative Site
Seoul
Novartis Investigative Site
Seoul
Novartis Investigative Site
Seoul
Novartis Investigative Site
Suwon Si
Novartis Investigative Site
Wonju
Romania
Novartis Investigative Site
Baia Mare
Novartis Investigative Site
Baia Mare
Novartis Investigative Site
Brasov
Novartis Investigative Site
Bucharest
Novartis Investigative Site
Bucuresti
Novartis Investigative Site
Buzau
Novartis Investigative Site
Craiova
Novartis Investigative Site
Iasi
Novartis Investigative Site
Iasi
Novartis Investigative Site
Timisoara
Russian Federation
Novartis Investigative Site
Chelyabinsk
Novartis Investigative Site
Ekaterinburg
Novartis Investigative Site
Ekaterinburg
Novartis Investigative Site
Ekaterinburg
Novartis Investigative Site
Ivanovo
Novartis Investigative Site
Izhevsk
Novartis Investigative Site
Kemerovo
Novartis Investigative Site
Kirov
Novartis Investigative Site
Korolev Moscow Region
Novartis Investigative Site
Krasnodar
Novartis Investigative Site
Moscow
Novartis Investigative Site
Moscow
Novartis Investigative Site
Moscow
Novartis Investigative Site
Moscow
Novartis Investigative Site
Moscow
Novartis Investigative Site
Moscow
Novartis Investigative Site
Novosibirsk
Novartis Investigative Site
Perm
Novartis Investigative Site
Petrozavodsk
Novartis Investigative Site
Rostov On Don
Novartis Investigative Site
Ryazan
Novartis Investigative Site
Saint Petersburg
Novartis Investigative Site
Saint Petersburg
Novartis Investigative Site
Saint Petersburg
Novartis Investigative Site
Saint Petersburg
Novartis Investigative Site
Saint Petersburg
Novartis Investigative Site
Saint-petersburg
Novartis Investigative Site
Samara
Novartis Investigative Site
Saratov
Novartis Investigative Site
Saratov
Novartis Investigative Site
Sochy
Novartis Investigative Site
St Petersburg
Novartis Investigative Site
St Petersburg
Novartis Investigative Site
St Petersburg
Novartis Investigative Site
St Petersburg
Novartis Investigative Site
St Petersburg
Novartis Investigative Site
Tomsk
Novartis Investigative Site
Ulyanovsk
Novartis Investigative Site
Vsevolozhsk
Novartis Investigative Site
Yaroslavl
Slovakia
Novartis Investigative Site
Banska Bystrica
Novartis Investigative Site
Bardejov
Novartis Investigative Site
Bardejovske Kupele
Novartis Investigative Site
Bratislava
Novartis Investigative Site
Bratislava
Novartis Investigative Site
Bratislava
Novartis Investigative Site
Bratislava
Novartis Investigative Site
Bratislava
Novartis Investigative Site
Bratislava
Novartis Investigative Site
Brezno
Novartis Investigative Site
Dolny Kubin
Novartis Investigative Site
Handlova
Novartis Investigative Site
Komarno
Novartis Investigative Site
Komarno
Novartis Investigative Site
Kosice
Novartis Investigative Site
Kosice
Novartis Investigative Site
Lucenec
Novartis Investigative Site
Nitra
Novartis Investigative Site
Nitra
Novartis Investigative Site
Nitra
Novartis Investigative Site
Nove Zamky
Novartis Investigative Site
Nove Zamky
Novartis Investigative Site
Piestany
Novartis Investigative Site
Povazska Bystrica
Novartis Investigative Site
Presov
Novartis Investigative Site
Rimavska Sobota
Novartis Investigative Site
Roznava
Novartis Investigative Site
Svidnik
Novartis Investigative Site
Trnava
Novartis Investigative Site
Turcianske Teplice
Novartis Investigative Site
Zilina
Slovenia
Novartis Investigative Site
Ljubljana
South Africa
Novartis Investigative Site
Cape Town
Novartis Investigative Site
Cape Town
Novartis Investigative Site
Cape Town
Novartis Investigative Site
George
Novartis Investigative Site
Soweto
Spain
Novartis Investigative Site
A Coruna
Novartis Investigative Site
Badalona
Novartis Investigative Site
Barcelona
Novartis Investigative Site
Barcelona
Novartis Investigative Site
Caceres
Novartis Investigative Site
Cordoba
Novartis Investigative Site
Hospitalet De Llobregat
Novartis Investigative Site
Huelva
Novartis Investigative Site
Madrid
Novartis Investigative Site
Madrid
Novartis Investigative Site
Malaga
Novartis Investigative Site
Reus
Novartis Investigative Site
Santander
Novartis Investigative Site
Santiago De Compostela
Novartis Investigative Site
Sevilla
Novartis Investigative Site
Sevilla
Novartis Investigative Site
Sevilla
Novartis Investigative Site
Valencia
Novartis Investigative Site
Zaragoza
Sweden
Novartis Investigative Site
Goteborg
Novartis Investigative Site
Lund
Novartis Investigative Site
Stockholm
Switzerland
Novartis Investigative Site
Basel
Novartis Investigative Site
Bern
Novartis Investigative Site
Geneve 14
Novartis Investigative Site
Lausanne
Novartis Investigative Site
Liestal
Novartis Investigative Site
Zuerich
Taiwan
Novartis Investigative Site
Hsinchu
Novartis Investigative Site
Kaohsiung
Novartis Investigative Site
Kaohsiung
Novartis Investigative Site
Keelung City
Novartis Investigative Site
Taichung
Novartis Investigative Site
Tainan
Novartis Investigative Site
Taipei
Novartis Investigative Site
Taoyuan
Novartis Investigative Site
Yilan
Turkey
Novartis Investigative Site
Ankara
Novartis Investigative Site
Haydarpasa Istanbul
Novartis Investigative Site
Istanbul
Novartis Investigative Site
Izmir
Novartis Investigative Site
Izmir
Novartis Investigative Site
Mersin
Novartis Investigative Site
Meselik
Novartis Investigative Site
Samsun
United Kingdom
Novartis Investigative Site
Birmingham
Novartis Investigative Site
Bournemouth
Novartis Investigative Site
Bristol
Novartis Investigative Site
Bromwich
Novartis Investigative Site
Cardiff
Novartis Investigative Site
Cardiff
Novartis Investigative Site
Chertsey
Novartis Investigative Site
Chesterfield
Novartis Investigative Site
Chichester
Novartis Investigative Site
Dorchester
Novartis Investigative Site
Dundee
Novartis Investigative Site
Edinburgh
Novartis Investigative Site
Glasgow
Novartis Investigative Site
Hardwick
Novartis Investigative Site
Harrow
Novartis Investigative Site
Leicester
Novartis Investigative Site
Liverpool
Novartis Investigative Site
London
Novartis Investigative Site
London
Novartis Investigative Site
London
Novartis Investigative Site
Londonderry
Novartis Investigative Site
Manchester
Novartis Investigative Site
Middlesbrough
Novartis Investigative Site
Middlesex
Novartis Investigative Site
Newcastle Upon Tyne
Novartis Investigative Site
Newport
Novartis Investigative Site
Norwich
Novartis Investigative Site
Plymouth
Novartis Investigative Site
Portadown
Novartis Investigative Site
Preston
Novartis Investigative Site
Rhyl
Novartis Investigative Site
Rochdale
Novartis Investigative Site
Sheffield
Novartis Investigative Site
Sunderland
Novartis Investigative Site
Swansea
Novartis Investigative Site
Taunton
Novartis Investigative Site
Tyne And Wear
Novartis Investigative Site
Wiltshire
Novartis Investigative Site
Wrexham
Time Frame
Start Date: 2019-12-12
Completion Date: 2026-02-26
Participants
Target number of participants: 8323
Treatments
Experimental: TQJ230
TQJ230 80 mg injected monthly administered subcutaneously
Placebo_comparator: Placebo
Monthly subcutaneous injections.
Authors
Jennifer G Robinson, Vikram Prasanna, David Sutton Jr, Howard Weintraub, Drew Purdy, Rony Gorges, Jean Foucauld, Daniel Duprez, Karen Aspry, Ghiath Mikdadi, Charles Treasure, Seth Baum, Jalal Ghali, Peter Fail, Adam Schussheim, Anil Chhabra, Christie Ballantyne, Dean Kereiakes, Jeffrey Anderson, Kevin Silver, Ijeoma Isiadinso, Mohsin Alhaddad, Jalal Abbas, Michael Chen, Paul Grena, Marc Bernstein, Paul Rosenblit, Ron Blankstein, Brendan Duffy, Ramin Manshadi, Denzil Moraes, Steven Krueger, Farhad Rafii, Kuruvilla Cheriparambil, William Eaves, Ahmed Arif, John Larry, Alexander White, Tuan-Huy Tran, Abha Khandelwal, Bruce Iteld, Paul Gurbel, Dale Presser, Melvin Martinez-Castrillon, Harry Colfer, Eulogio Sanchez, Tariq Haddad, Peter Bressler, David Hotchkiss, Vikram Arora, Robert Fishberg, Siby George Ayalloore, Eugenia Gianos, Dennis Bruemmer, Fahed Bitar, Bhola Rama, Freny Mody, Barry Harris, Joseph Soufer, Mary McGowan, Frank Voelker, John Petersen II, Joe L Hargrove, Linda Hemphill, Dylan Steen, Michael Shapiro, MacRae Linton, John Pasquini, Albert Lopez, Peter Fattal, Thomas Knickelbine, Billy Jones, Ferris George, Alan Miller, Shamaila Aslam, Joseph Miller, Herman Cheek, Naseem Jaffrani, Sean Donahoe, Julie Clary, Keith Friedman, John Hallgren, Ernest Thompson, Mehrdad Ariani, Vernon Hunter, Bruce Gebhardt, Felton Anderson, Sidney Gorton, Norman Lepor, Alan Brown, Lois Steele, Ranchhod Khant, Sajan Rao, Joel Landzberg, Jagadeesh Ganji, Mahmoud Atieh, Julian Javier, Parveen Garg, Charles Lovell, Edward Teufel, Paul Thompson, Anthony DeMaria, Jonathan Purnell, Hugh Moore, Archna Bajaj, Thorsten Leucker, Eveline Stock, Jose Vazquez-Tanus, Marjan Mujib, Vishal Gupta
Sponsors
Leads: Novartis Pharmaceuticals