Ampullary Cancer Overview

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Learn About Ampullary Cancer

What is the definition of Ampullary Cancer?
Ampullary cancer is a rare cancer of the ampulla of Vater. The ampulla of Vater is a small opening that is part of the digestive system located by the small intestine where the bile duct and pancreatic duct join. Ampullary cancer can also form near or spread to the liver and pancreas.
What are the symptoms of Ampullary Cancer?
Symptoms of ampullary cancer include jaundice (yellowing of the skin and eyes); itchy skin; anemia; fever; loss of appetite; nausea; vomiting; abdominal pain; gastrointestinal bleeding; rectal bleeding; back pain; pancreatitis; pale, greasy stools; diarrhea; and weight loss.
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What are the current treatments for Ampullary Cancer?
Treatments for ampullary cancer include minimally-invasive surgery (endoscopic resection); laser ablation; open surgery (Whipple procedure, or pancreaticoduodenectomy, in which the head of the pancreas, duodenum, gallbladder, part of the common bile duct, part of the stomach, and nearby lymph nodes are removed); stent placement to drain bile and pancreatic enzymes; chemotherapy; and combined chemotherapy and radiation therapy.
Who are the top Ampullary Cancer Local Doctors?
Laura L. Mcilwain, PA
Physician Assistant
Laura L. Mcilwain, PA
Physician Assistant

Wake Forest University Health Sciences

365 Brookdale Dr, 
Statesville, NC 
 (1.0 mi)
704-872-3630
Languages Spoken:
English
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Accepting New Patients

Laura Mcilwain is a Physician Assistant in Statesville, North Carolina. Mcilwain and is rated as an Experienced provider by MediFind in the treatment of Ampullary Cancer. Her top areas of expertise are Ampullary Cancer, Gallbladder Adenocarcinoma, Gastroesophageal Junction Cancer, and Pancreatic Ductal Adenocarcinoma. Mcilwain is currently accepting new patients.

Dr. Perry Y. Shen
General Surgery | Surgical Oncology
Dr. Perry Y. Shen
General Surgery | Surgical Oncology

Wake Forest University Health Sciences

Medical Ctr Blvd, 
Winston Salem, NC 
 (40.5 mi)
336-716-2734
Languages Spoken:
English
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Accepting New Patients

Perry Shen is a General Surgeon and a Surgical Oncologist in Winston Salem, North Carolina. Dr. Shen and is rated as an Advanced provider by MediFind in the treatment of Ampullary Cancer. His top areas of expertise are Cholangiocarcinoma (Bile Duct Cancer), Gallbladder Cancer, Gallbladder Disease, Pancreatectomy, and Hepatectomy. Dr. Shen is currently accepting new patients.

 
 
 
 
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Dr. Michael J. Beckman
Surgical Oncology | General Surgery
Dr. Michael J. Beckman
Surgical Oncology | General Surgery

Carolinas Physicians Network Inc

200 Medical Park Dr, Suite 430, 
Concord, NC 
 (28.8 mi)
704-403-7070
Languages Spoken:
English
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Accepting New Patients
Offers Telehealth

Michael Beckman is a Surgical Oncologist and a General Surgeon in Concord, North Carolina. Dr. Beckman and is rated as an Experienced provider by MediFind in the treatment of Ampullary Cancer. His top areas of expertise are Pancreatic Cancer, Gastrointestinal Stromal Tumor, Hereditary Pancreatitis, Pancreaticoduodenectomy, and Hepato-Pancreato-Biliary Surgery. Dr. Beckman is currently accepting new patients.

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What are the latest Ampullary Cancer Clinical Trials?
The ADAPTA Study: ADjuvant chemotherAPy After Curative Intent resecTion of Ampullary Cancer. A Pan-European Prospective Multicenter Double Single Arm Cohort Study.
The ADAPTA Study: ADjuvant chemotherAPy After Curative Intent resecTion of Ampullary Cancer. A Pan-European Prospective Multicenter Double Single Arm Cohort Study.
Enrollment Status: Recruiting
Publish Date: October 05, 2023
Intervention Type: Drug

Summary: Ampullary adenocarcinoma (AAC) is a rare gastrointestinal cancer with varying survival rates, particularly the aggressive pancreatobiliary (PB) subtype. Adjuvant therapy benefits only PB and mixed subtype patients, while prospective studies are required for validation. A study proposes tailored adjuvant treatments (CAPOX for intestinal subtype, FOLFIRINOX for PB and mixed subtypes) based on histop...

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