Autoimmune Polyglandular Syndrome Type 2 Overview

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Learn About Autoimmune Polyglandular Syndrome Type 2

What is the definition of Autoimmune Polyglandular Syndrome Type 2?
Autoimmune polyglandular syndrome type 2 is an autoimmune disorder that affects many hormone-producing (endocrine) glands. It is characterized by the presence of Addison's disease along with autoimmune thyroid disease and/or type 1 diabetes. Affected individuals may also have problems with other endocrine glands and other common features include primary hypogonadism, myasthenia gravis, and celiac disease. Autoimmune polyglandular syndrome type 2 is diagnosed in adulthood. The cause of Autoimmune polyglandular syndrome type 2 is unknown, although it may involve a combination of genetic and environmental factors. This condition occurs more often in women than men. Currently, there are no unique tests to detect APS-2, but testing for autoantibodies may be helpful in assessing disease risk, since the relevant autoantibodies (such as antibodies to thyroid peroxidase in autoimmune thyroid disease, or to glutamic acid decarboxylase in type 1 diabetes) are frequently detectable years before disease onset.
What are the alternative names for Autoimmune Polyglandular Syndrome Type 2?
  • Autoimmune polyglandular syndrome type 2
  • APS2
  • Autoimmune polyendocrine syndrome type 2
  • Autoimmune polyglandular syndrome type II
  • Diabetes mellitus, Addison's disease, myxedema
  • Multiple endocrine deficiency syndrome, type 2
  • PGA 2
  • PGA-II
  • Polyglandular autoimmune syndrome, type 2
  • Polyglandular deficiency syndrome type 2
  • Schmidt syndrome
  • Schmidt's syndrome
Who are the top Autoimmune Polyglandular Syndrome Type 2 Local Doctors?
Experienced in Autoimmune Polyglandular Syndrome Type 2
Dr. James W. Findling
Endocrinology
Experienced in Autoimmune Polyglandular Syndrome Type 2
Dr. James W. Findling
Endocrinology

Froedtert Andthe Medical College Of Wisconsin Community Physicians Inc

W129n7055 Northfield Dr, 
Menomonee Falls, WI 
 (147.9 mi)
262-253-5400
Languages Spoken:
English
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Accepting New Patients
Offers Telehealth

James Findling is an Endocrinologist in Menomonee Falls, Wisconsin. Dr. Findling and is rated as an Experienced provider by MediFind in the treatment of Autoimmune Polyglandular Syndrome Type 2. His top areas of expertise are Cushing's syndrome, Cushing's disease, Addison's Disease, Secondary Adrenal Insufficiency, and Hormone Replacement Therapy (HRT). Dr. Findling is currently accepting new patients.

Distinguished in Autoimmune Polyglandular Syndrome Type 2
Dr. Clarisse Ethridge
Endocrinology
Distinguished in Autoimmune Polyglandular Syndrome Type 2
Dr. Clarisse Ethridge
Endocrinology

Dean Health Systems Inc

1821 S Stoughton Rd, 
Madison, WI 
 (143.1 mi)
608-260-6000
Languages Spoken:
English
Offers Telehealth

Clarisse Ethridge is an Endocrinologist in Madison, Wisconsin. Dr. Ethridge and is rated as a Distinguished provider by MediFind in the treatment of Autoimmune Polyglandular Syndrome Type 2. Her top areas of expertise are Thyroid Cancer, Anaplastic Thyroid Cancer, Papillary Thyroid Cancer, and Medullary Thyroid Carcinoma.

 
 
 
 
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Distinguished in Autoimmune Polyglandular Syndrome Type 2
Dr. Diana P. Choles
Internal Medicine
Distinguished in Autoimmune Polyglandular Syndrome Type 2
Dr. Diana P. Choles
Internal Medicine

Dean Health Systems Inc

752 N High Point Rd, 
Madison, WI 
 (143.7 mi)
608-824-4000
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Diana Choles is an Internal Medicine provider in Madison, Wisconsin. Dr. Choles and is rated as a Distinguished provider by MediFind in the treatment of Autoimmune Polyglandular Syndrome Type 2. Her top areas of expertise are Autoimmune Polyglandular Syndrome Type 2, IPEX Syndrome, Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED), and Type 1 Diabetes (T1D). Dr. Choles is currently accepting new patients.

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What are the latest Autoimmune Polyglandular Syndrome Type 2 Clinical Trials?
The Natural History and Pathogenesis of Human Fungal Infections
The Natural History and Pathogenesis of Human Fungal Infections
Enrollment Status: Recruiting
Publish Date: February 21, 2025

Background: - The immune system is made up of special cells, tissues, and organs that fight infections. Problems with this system may lead to frequent, severe, or unusual fungal infections. These infections are often difficult to treat. Researchers want to collect blood and tissue samples from people who have unusual, persistent or severe fungal infections or immune problems that increase the risk of these in...

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A Phase 2 Open-Label Study to Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata
A Phase 2 Open-Label Study to Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata
Enrollment Status: Recruiting
Publish Date: December 30, 2024
Intervention Type: Drug
Study Phase: Phase 2

Background: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a problem of the immune system. In people with APECED, the immune system makes a mistake and attacks the body. Some people with APECED have a type of hair loss called alopecia areata (AA). No drugs are approved to treat AA.

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center