B-Cell Lymphoma Overview

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Learn About B-Cell Lymphoma

What is the definition of B-Cell Lymphoma?
B-cell lymphoma refers to types of non-Hodgkin lymphoma that are characterized by abnormalities of the "B-cells" (a type of white blood cell that makes antibodies to help fight infection). The condition may grow and spread slowly with few symptoms (also known as indolent lymphoma) or may be very aggressive with severe symptoms. When present, signs and symptoms may include swollen lymph nodes in the neck, armpit, or groin; abdominal pain; fatigue; fever; night sweats; and/or weight loss. The underlying cause of B-cell lymphoma is poorly understood. However, the condition can be associated with genetic abnormalities, environmental factors, viruses, immunodeficiency states, and connective-tissue disorders.
What are the alternative names for B-Cell Lymphoma?
  • B-cell lymphoma
  • Lymphoma, B-Cell
Who are the top B-Cell Lymphoma Local Doctors?
Experienced in B-Cell Lymphoma
Dr. Keith J. August
Pediatric Hematology Oncology | Hematology | Oncology
Experienced in B-Cell Lymphoma
Dr. Keith J. August
Pediatric Hematology Oncology | Hematology | Oncology
2401 Gillham Rd, 
Kansas City, MO 
 (3.4 mi)
816-302-6808
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Keith August is a Pediatric Hematologist Oncology specialist and a Hematologist in Kansas City, Missouri. Dr. August and is rated as an Experienced provider by MediFind in the treatment of B-Cell Lymphoma. His top areas of expertise are Acute Lymphoblastic Leukemia (ALL), Leukemia, Infantile Neutropenia, Bone Marrow Aspiration, and Bone Marrow Transplant. Dr. August is currently accepting new patients.

Experienced in B-Cell Lymphoma
Dr. Anthony D. Sung
Hematology Oncology | Hematology | Oncology
Experienced in B-Cell Lymphoma
Dr. Anthony D. Sung
Hematology Oncology | Hematology | Oncology

University Of Kansas Hospital Authority

2650 Shawnee Mission Pkwy, 
Westwood, KS 
 (5.7 mi)
913-588-7750
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Anthony Sung is a Hematologist Oncology specialist and a Hematologist in Westwood, Kansas. Dr. Sung and is rated as an Experienced provider by MediFind in the treatment of B-Cell Lymphoma. His top areas of expertise are Chronic Graft Versus Host Disease (cGvHD), Graft Versus Host Disease (GvHD), Acute Myeloid Leukemia (AML), Multiple Myeloma, and Bone Marrow Transplant. Dr. Sung is currently accepting new patients.

 
 
 
 
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Experienced in B-Cell Lymphoma
Dr. Mohammad Mozayen
Hematology Oncology | Oncology | Hematology
Experienced in B-Cell Lymphoma
Dr. Mohammad Mozayen
Hematology Oncology | Oncology | Hematology

Midwest Oncology Associates LLC

2316 E Meyer Blvd, Research Medical Center, 
Kansas City, MO 
 (8.3 mi)
816-276-4000
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Mohammad Mozayen is a Hematologist Oncology specialist and an Oncologist in Kansas City, Missouri. Dr. Mozayen and is rated as an Experienced provider by MediFind in the treatment of B-Cell Lymphoma. His top areas of expertise are Neuroendocrine Tumor, Lung Cancer, Childhood Iron Deficiency Anemia, and Familial Colorectal Cancer. Dr. Mozayen is currently accepting new patients.

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What are the latest B-Cell Lymphoma Clinical Trials?
Phase 1/2 Dose Escalation Study of CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies
Phase 1/2 Dose Escalation Study of CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies
Enrollment Status: Recruiting
Publish Date: February 26, 2025
Intervention Type: Drug, Biological
Study Phase: Phase 1/Phase 2

Background: Acute lymphoblastic leukemia (ALL) is the most common cancer in children. About 90% of children and young adults who are treated for ALL can now be cured. But if the disease comes back, the survival rate drops to less than 50%. Better treatments are needed for ALL relapses.

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A Prospective, Open-Label, Single-Arm, Phase II Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With Diffuse Large B-Cell Lymphoma (ACRUE)
A Prospective, Open-Label, Single-Arm, Phase II Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With Diffuse Large B-Cell Lymphoma (ACRUE)
Enrollment Status: Recruiting
Publish Date: February 26, 2025
Intervention Type: Biological, Drug
Study Phase: Phase 2

Summary: The study will measure the safety, tolerability, and efficacy with acalabrutinib in combination with rituximab in treatment-naïve elderly and/or frail patients with diffuse large B-cell lymphoma (DLBCL), who are otherwise unsuitable for standard front line chemoimmunotherapy treatments.

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center