Bowen's Disease Overview

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Learn About Bowen's Disease

What is the definition of Bowen's Disease?
A form of squamous cell carcinoma in situ. It is a distinct clinicopathological entity and arises from the skin or the mucocutaneous junction. It affects predominantly white males in their 6-8th decades of life. Exposed and non-exposed skin sites are equally affected. UV damage and ingestion of inorganic arsenic may play a role in the development of the disease. On the skin surface, it presents as a single or multiple erythematous, scaly, keratotic patches or plaques. The clinical entity of erythroplasia of Queyrat is regarded as Bowen disease of the penis and it presents as an asymptomatic, red, circumscribed plaque. Morphologically, Bowen disease is characterized by the presence of hyperkeratosis, parakeratosis, dyskeratosis, and acanthosis. The keratotic squamous cells are atypical and display hyperchromatism and abnormal mitotic figures. The dermoepidermal basement membrane is intact. Complete surgical removal of the lesion may be curative.
What are the alternative names for Bowen's Disease?
  • Bowen's disease
Who are the top Bowen's Disease Local Doctors?
Dr. Kyle A. Anderson
Dermatology
Dr. Kyle A. Anderson
Dermatology

Kansas Medical Clinic PA

11301 Nall Ave, Suite 205, 
Leawood, KS 
 (4.3 mi)
913-451-5934
Languages Spoken:
English
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Accepting New Patients

Kyle Anderson is a Dermatologist in Leawood, Kansas. Dr. Anderson and is rated as an Advanced provider by MediFind in the treatment of Bowen's Disease. His top areas of expertise are Lamellar Ichthyosis, Syringocystadenoma Papilliferum, Syringoma, and Sebaceous Adenoma. Dr. Anderson is currently accepting new patients.

Dr. Wenfei Xie
Dermatology
Dr. Wenfei Xie
Dermatology

Kansas City Skin And Cancer Center LLC

9301 W 74th St, Suite 230, 
Shawnee Mission, KS 
 (1.5 mi)
816-584-8100
Languages Spoken:
English, Mandarin
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Accepting New Patients

Wenfei Xie is a Dermatologist in Shawnee Mission, Kansas. Dr. Xie and is rated as an Experienced provider by MediFind in the treatment of Bowen's Disease. Her top areas of expertise are Neurocutaneous Melanosis, Familial Atypical Multiple Mole Melanoma Syndrome, Giant Congenital Nevus, and Giant Congenital Melanocytic Nevus. Dr. Xie is currently accepting new patients.

 
 
 
 
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Teresa A. Corrigan, NP
Nurse Practitioner | Dermatology
Teresa A. Corrigan, NP
Nurse Practitioner | Dermatology

Kansas Medical Clinic PA

5820 Lamar Ave, Suite 200, 
Mission, KS 
 (2.9 mi)
913-631-6330
Languages Spoken:
English
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Accepting New Patients

Teresa Corrigan is a Nurse Practitioner specialist and a Dermatologist in Mission, Kansas. Corrigan and is rated as an Experienced provider by MediFind in the treatment of Bowen's Disease. Her top areas of expertise are Actinic Keratosis, Sunburn, Warts, and Seborrheic Keratosis. Corrigan is currently accepting new patients.

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What are the latest Bowen's Disease Clinical Trials?
Evaluation of the Clinical Utility of a New Diagnostic Support Tool, Based on Electrical Impedance Spectroscopy (NEVISENSE), for Keratinocyte Skin Cancer
Evaluation of the Clinical Utility of a New Diagnostic Support Tool, Based on Electrical Impedance Spectroscopy (NEVISENSE), for Keratinocyte Skin Cancer
Enrollment Status: Recruiting
Publish Date: December 11, 2024
Intervention Type: Device
Study Phase: Not Applicable

Summary: This is a prospective study to assess efficacy of the Nevisense device in identifying keratinocyte skin cancer (KC) in patients suspected of having skin cancer based on the initial physician's assessment. All skin lesions with a suspicion of Basal cell carcinoma (BCC), Invasive Squamos cell Carcinoma (iSCC), Bowen's disease (BD) or actinic keratosis (AK) and destined for excision or biopsy for fur...

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Surgical Excision Versus Photodynamic Therapy and Topical 5-fluorouracil in Treatment of Bowen's Disease: a Multicenter Randomized Controlled Trial
Surgical Excision Versus Photodynamic Therapy and Topical 5-fluorouracil in Treatment of Bowen's Disease: a Multicenter Randomized Controlled Trial
Who is this study for: Adult patients with Bowen's disease
Enrollment Status: Recruiting
Publish Date: October 27, 2020
Intervention Type: Drug, Other
Study Drugs: Methyl Aminolevulinate, 5Fluorouracil
Study Phase: Phase 4

Objective: The aim of this study is 1) to evaluate the (cost)effectiveness of 5FU and PDT compared to SE in BD and 2) to compare the effectiveness of 5FU with that of PDT. With a better understanding of the (cost)effectiveness of alternative treatment options, the investigators will supply the necessary evidence for national and international guidelines, to achieve more uniformity in treatment of BD. Study d...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center