Bronchiectasis Overview
Learn About Bronchiectasis
Bronchiectasis is a disease in which the large airways in the lungs are damaged. This causes the airways to become permanently wider.
Bronchiectasis can be present at birth or infancy or develop later in life.
Acquired bronchiectasis; Congenital bronchiectasis; Chronic lung disease - bronchiectasis
Bronchiectasis is often caused by inflammation or infection of the airways that keeps coming back.
Sometimes it begins in childhood after having a severe lung infection or inhaling a foreign object. Breathing in food particles can also lead to this condition.
Other causes of bronchiectasis can include:
- Cystic fibrosis, a disease that causes thick, sticky mucus to build up in the lungs
- Autoimmune disorders, such as rheumatoid arthritis, Sjögren syndrome or inflammatory bowel disease
- Allergic lung diseases
- Leukemia and related cancers
- Immune deficiency syndromes
- Primary ciliary dyskinesia (another congenital disease)
- Infection with non-tuberculous mycobacteria
- As a complication of bronchiolitis obliterans
- Asthma or chronic obstructive lung disease (uncommon)
Symptoms develop over time. They may occur months or years after the event that causes the bronchiectasis.
Long-term (chronic) cough with large amounts of foul smelling sputum is the main symptom of bronchiectasis. Other symptoms may include:
- Breath odor
- Coughing up blood (less common in children)
- Fatigue
- Paleness
- Shortness of breath that gets worse with exercise
- Weight loss
- Wheezing
- Low grade fever and night sweats
- Clubbing of fingers (rare, depends on cause)
Treatment is aimed at:
- Controlling infections and sputum
- Relieving airway blockage
- Preventing the problem from becoming worse
- Treating the underlying cause (for example modulator therapy for people with cystic fibrosis)
Daily drainage to remove sputum is part of treatment. A respiratory therapist can show the person coughing exercises that will help.
Medicines are often prescribed. These include:
- Antibiotics to treat infections
- Bronchodilators to open up airways
- Expectorants to help loosen and cough up thick sputum
Surgery to remove (resect) the lung may be needed if medicine does not work and the disease is in a small area, or if the person has a lot of bleeding in the lungs. It is more commonly considered if there is no genetic or acquired predisposition to bronchiectasis (for example, more likely to consider if there is bronchiectasis in one segment of the lung only because of prior obstruction).
In severe cases, lung transplantation might be needed.
Pamela Wells is a Radiologist in Jackson, Tennessee. Dr. Wells and is rated as an Advanced provider by MediFind in the treatment of Bronchiectasis. Her top areas of expertise are Chronic Cough, Breast Lump, Vertigo, and Lung Nodules. Dr. Wells is currently accepting new patients.
Mid-South Imaging And Therapeutics, P.A.
Paul Tanner is a Radiologist in Huntingdon, Tennessee. Dr. Tanner and is rated as an Experienced provider by MediFind in the treatment of Bronchiectasis. His top areas of expertise are Vertigo, Chronic Cough, Lung Nodules, and Carbuncle. Dr. Tanner is currently accepting new patients.
Jackson Clinic PA
Luis Pagoaga is a Family Medicine provider in Medina, Tennessee. Dr. Pagoaga and is rated as an Experienced provider by MediFind in the treatment of Bronchiectasis. His top areas of expertise are Chronic Cough, Vertigo, Fainting, and Sinusitis. Dr. Pagoaga is currently accepting new patients.
The outlook depends on the specific cause of the disease. With treatment, most people live without major disability and the disease progresses slowly.
Complications of bronchiectasis may include:
- Cor pulmonale
- Coughing up blood
- Low oxygen levels (in severe cases)
- Recurrent pneumonia
- Depression
Contact your provider if:
- Chest pain or shortness of breath gets worse
- There is a change in the color or amount of phlegm you cough up, or if it is bloody
- Other symptoms get worse or do not improve with treatment
You can reduce your risk by promptly treating lung infections.
Childhood vaccines a yearly flu vaccine, and COVID-19 vaccines help reduce the chance of some infections. Avoiding upper respiratory infections, smoking, and pollution may also reduce your risk of getting this infection.
Summary: ACT18018 is a multinational, randomized, double-blind, placebo-controlled, parallel-group, Phase 2 study with 3 treatment groups. The purpose of this study is to evaluate efficacy, safety and tolerability with 2 dosing regimens of itepekimab compared with placebo in male and/or female participants with NCFB aged 18 years of age up to 85 years of age (inclusive). Study details include: * The study ...
Summary: Chronic inflammatory pulmonary diseases including chronic obstructive pulmonary disease (COPD), interstitial lung diseases (ILD), bronchiectasis, and cystic fibrosis (CF) are characterized by lung inflammation and remodelling. Clinical, functional, microbiological, biological, pathological and prognosis features are highly variable and heterogeneous. A precise phenotyping is a key-element to bette...
Published Date: July 31, 2022
Published By: Denis Hadjiliadis, MD, MHS, Paul F. Harron, Jr. Professor of Medicine, Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Chang AB, Redding GJ. Bronchiectasis and chronic suppurative lung disease. In: Wilmott RW, Deterding R, Li A, et al, eds. Kendig's Disorders of the Respiratory Tract in Children. 9th ed. Philadelphia, PA: Elsevier; 2019:chap 26.
O'Donnell AE. Bronchiectasis, atelectasis, cysts, and localized lung disorders. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 84.
Solomon GM, Chan ED. Bronchiectasis. In: Broaddus VC, Ernst JD, King TE, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 69.