Childhood Hypophosphatasia (HPP) Overview

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Learn About Childhood Hypophosphatasia (HPP)

What is the definition of Childhood Hypophosphatasia (HPP)?
Childhood hypophosphatasia is a form of hypophosphatasia, a rare condition that affects the bones. Symptoms vary but may include delayed motor milestones; low bone mineral density for age; early loss of baby teeth (before age 5); bone and joint pain; short stature; a waddling gait; skeletal malformations; and/or unexplained broken bones. The forms of hypophosphatasia that develop during childhood are generally more mild than those that appear in infancy. Childhood hypophosphatasia is caused by changes in the ALPL gene and can be inherited in an autosomal dominant or autosomal recessive manner.
What are the alternative names for Childhood Hypophosphatasia (HPP)?
  • Childhood hypophosphatasia
  • Childhood-onset Rathburn disease
  • Childhood-onset hypophosphatasia
  • Childhood-onset phosphoethanolaminuria
Who are the top Childhood Hypophosphatasia (HPP) Local Doctors?
Experienced in Childhood Hypophosphatasia (HPP)
Dr. Muhammad T. Randhawa
Internal Medicine
Experienced in Childhood Hypophosphatasia (HPP)
Dr. Muhammad T. Randhawa
Internal Medicine
434 Monroe Ave, 
Hornell, NY 
 (41.6 mi)
607-324-7740
Languages Spoken:
English
Offers Telehealth

Muhammad Randhawa is an Internal Medicine provider in Hornell, New York. Dr. Randhawa and is rated as an Experienced provider by MediFind in the treatment of Childhood Hypophosphatasia (HPP). His top areas of expertise are Chronic Obstructive Pulmonary Disease (COPD), Lung Metastases, Alzheimer's Disease, and Sepsis.

Advanced in Childhood Hypophosphatasia (HPP)
Dr. Sarvesh Rajan
Endocrinology
Advanced in Childhood Hypophosphatasia (HPP)
Dr. Sarvesh Rajan
Endocrinology

Dubois Regional Medical Center

145 Hospital Ave, Suite 101, 
Du Bois, PA 
 (60.1 mi)
814-375-4089
Languages Spoken:
English
See accepted insurances

Sarvesh Rajan is an Endocrinologist in Du Bois, Pennsylvania. Dr. Rajan and is rated as an Advanced provider by MediFind in the treatment of Childhood Hypophosphatasia (HPP). His top areas of expertise are Thyroid Nodule, Thyroid Cancer, Follicular Thyroid Cancer, and Papillary Thyroid Cancer.

 
 
 
 
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Advanced in Childhood Hypophosphatasia (HPP)
Dr. Mohammad A. Quasem
Nephrology
Advanced in Childhood Hypophosphatasia (HPP)
Dr. Mohammad A. Quasem
Nephrology

United Health Services Hospitals, Inc.

54 Main St, 
Candor, NY 
 (91.9 mi)
607-659-7272
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Mohammad Quasem is a Nephrologist in Candor, New York. Dr. Quasem and is rated as an Advanced provider by MediFind in the treatment of Childhood Hypophosphatasia (HPP). His top areas of expertise are Renovascular Hypertension, Nephrosclerosis, Acute Kidney Failure, End-Stage Renal Disease (ESRD), and Gastrostomy.

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What are the latest Childhood Hypophosphatasia (HPP) Clinical Trials?
Universal Genomic Newborn Screening in the Wallonia-Brussels Federation: Baby Detect
Universal Genomic Newborn Screening in the Wallonia-Brussels Federation: Baby Detect
Enrollment Status: Recruiting
Publish Date: February 12, 2025

Summary: Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions. With a simple blood test, rare genetic conditions can be easily detected, and the early start of transformative treatment will help avoid severe disabilities and increase the quality of life. Baby Detect Project is an innovative NBS program using a pane...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center