Chromosome 20 Trisomy Overview
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Learn About Chromosome 20 Trisomy
What is the definition of Chromosome 20 Trisomy?
Chromosome 20 trisomy, (also called trisomy 20) is a condition in which a fetus or individual has an extra full or partial copy of chromosome 20 in some or all of of his/her cells. The presence of an extra copy of only part of chromosome 20 is called partial trisomy 20; and an extra copy of chromosome 20 in only some of a person's cells is called mosaic trisomy 20. Mosaic trisomy 20 is the most common type of Chromosome 20 trisomy and is one of the more common chromosomal abnormalities found during prenatal diagnostic testing. However, features that have been reported include spinal abnormalities (including spinal stenosis, vertebral fusion, and kyphosis), hypotonia (decreased muscle tone), lifelong constipation, sloped shoulders, and significant learning disabilities despite normal intelligence. Trisomy 20 usually results from an error that occurs when an egg or sperm cell develops (before fertilization); mosaic trisomy 20 usually results from errors in cell division soon after fertilization.
What are the alternative names for Chromosome 20 Trisomy?
- Chromosome 20 trisomy
- Mosaic trisomy 20
- Trisomy 20
- Trisomy 20 mosaicism
- Trisomy chromosome 20
Who are the top Chromosome 20 Trisomy Local Doctors?
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What are the latest Chromosome 20 Trisomy Clinical Trials?
Who are the sources who wrote this article ?
Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center
What are the Latest Advances for Chromosome 20 Trisomy?
Complete cytogenetic discrepancy between cultured amniocytes and uncultured amniocytes is common in mosaic trisomy 20 at amniocentesis with positive conventional cytogenetic analysis and negative chromosomal microarray analysis.
Journal: Taiwanese journal of obstetrics & gynecology
Published: July 19, 2024
Application of quantitative fluorescent polymerase chain reaction on the DNA extracted from cultured amniocytes for rapid exclusion of uniparental disomy 20 in case of mosaic trisomy 20 at amniocentesis.
Journal: Taiwanese journal of obstetrics & gynecology
Published: July 19, 2024
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Rare Case of a 20p13 Duplication Trisomy With Craniostenosis.
Journal: Cureus
Published: June 08, 2024