Congenital Insensitivity to Pain with Anhidrosis Overview

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Learn About Congenital Insensitivity to Pain with Anhidrosis

What is the definition of Congenital Insensitivity to Pain with Anhidrosis?
Congenital insensitivity to pain with anhidrosis (CIPA) also known as hereditary sensory and autonomic neuropathy type IV, is an inherited disease where there is an inability to feel pain and temperature, and decreased or absent sweating (anhidrosis). The signs and symptoms of CIPA usually appear at birth or during infancy. The inability to feel pain and temperature often leads to repeated, severe injuries and unintentional self-injury is common. People with CIPA may also heal slowly from skin and bone injuries, which can lead to chronic bone infections (osteomyelitis) or a condition called Charcot joints. Absent sweating can cause recurrent, high fevers (hyperpyrexia) and seizures brought on by high temperature (febrile seizures). Other features may include dental caries, difficulty controlling urine and defecating (urine and fecal incontinence), behavioral or emotional problems and intellectual disability. CIPA is caused by changes in the NTRK1 gene. Inheritance is autosomal recessive.
What are the alternative names for Congenital Insensitivity to Pain with Anhidrosis?
  • Congenital insensitivity to pain with anhidrosis
  • CIPA
  • Familial dysautonomia, type 2
  • Familial dysautonomia, type II
  • HSAN 4
  • HSAN IV
  • HSNAN4
  • Hereditary sensory and autonomic neuropathy 4
  • Hereditary sensory neuropathy type IV
  • Insensitivity to pain, congenital, with anhidrosis
  • Neuropathy, congenital sensory, with anhidrosis
Who are the top Congenital Insensitivity to Pain with Anhidrosis Local Doctors?
Experienced in Congenital Insensitivity to Pain with Anhidrosis
Dr. James H. Gilroy
Internal Medicine
Experienced in Congenital Insensitivity to Pain with Anhidrosis
Dr. James H. Gilroy
Internal Medicine
277 Post Road, 
Moody, ME 
 (7.5 mi)
207-646-8386
Languages Spoken:
English
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James Gilroy is an Internal Medicine provider in Moody, Maine. Dr. Gilroy and is rated as an Experienced provider by MediFind in the treatment of Congenital Insensitivity to Pain with Anhidrosis. His top areas of expertise are Familial Hypertension, Hypertension, Glucocorticoid-Remediable Aldosteronism, and Type 2 Diabetes (T2D). Dr. Gilroy is currently accepting new patients.

Experienced in Congenital Insensitivity to Pain with Anhidrosis
Dr. Peter J. Morin
Neurology
Experienced in Congenital Insensitivity to Pain with Anhidrosis
Dr. Peter J. Morin
Neurology

York Hospital

233 York St A, Neurology Associates Of York Hospital, 
York, ME 
 (10.1 mi)
207-351-3987
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Peter Morin is a Neurologist in York, Maine. Dr. Morin and is rated as an Experienced provider by MediFind in the treatment of Congenital Insensitivity to Pain with Anhidrosis. His top areas of expertise are Dementia, Parkinson's Disease, Alzheimer's Disease, and Seizures. Dr. Morin is currently accepting new patients.

 
 
 
 
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Experienced in Congenital Insensitivity to Pain with Anhidrosis
Dr. Richard S. Finkelman
Neurology
Experienced in Congenital Insensitivity to Pain with Anhidrosis
Dr. Richard S. Finkelman
Neurology

Wentworth Douglass Physician Corporation

10 Members Way, 300 Coastal Neurology Services, 
Dover, NH 
 (10.4 mi)
603-749-0913
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Richard Finkelman is a Neurologist in Dover, New Hampshire. Dr. Finkelman and is rated as an Experienced provider by MediFind in the treatment of Congenital Insensitivity to Pain with Anhidrosis. His top areas of expertise are Seizures, Memory Loss, Chronic Inflammatory Demyelinating Polyneuropathy, and Transient Ischemic Attack (TIA). Dr. Finkelman is currently accepting new patients.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center