Congenital Insensitivity to Pain with Anhidrosis Overview

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Learn About Congenital Insensitivity to Pain with Anhidrosis

What is the definition of Congenital Insensitivity to Pain with Anhidrosis?
Congenital insensitivity to pain with anhidrosis (CIPA) also known as hereditary sensory and autonomic neuropathy type IV, is an inherited disease where there is an inability to feel pain and temperature, and decreased or absent sweating (anhidrosis). The signs and symptoms of CIPA usually appear at birth or during infancy. The inability to feel pain and temperature often leads to repeated, severe injuries and unintentional self-injury is common. People with CIPA may also heal slowly from skin and bone injuries, which can lead to chronic bone infections (osteomyelitis) or a condition called Charcot joints. Absent sweating can cause recurrent, high fevers (hyperpyrexia) and seizures brought on by high temperature (febrile seizures). Other features may include dental caries, difficulty controlling urine and defecating (urine and fecal incontinence), behavioral or emotional problems and intellectual disability. CIPA is caused by changes in the NTRK1 gene. Inheritance is autosomal recessive.
What are the alternative names for Congenital Insensitivity to Pain with Anhidrosis?
  • Congenital insensitivity to pain with anhidrosis
  • CIPA
  • Familial dysautonomia, type 2
  • Familial dysautonomia, type II
  • HSAN 4
  • HSAN IV
  • HSNAN4
  • Hereditary sensory and autonomic neuropathy 4
  • Hereditary sensory neuropathy type IV
  • Insensitivity to pain, congenital, with anhidrosis
  • Neuropathy, congenital sensory, with anhidrosis
Who are the top Congenital Insensitivity to Pain with Anhidrosis Local Doctors?
Dr. Florence Barricelli
Internal Medicine
Dr. Florence Barricelli
Internal Medicine

Chs Physician Partners PC

146 A Manetto Hill Rd, Suite 205, 
Plainview, NY 
 (3.4 mi)
516-302-8530
Languages Spoken:
English
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Florence Barricelli is an Internal Medicine provider in Plainview, New York. Dr. Barricelli and is rated as an Experienced provider by MediFind in the treatment of Congenital Insensitivity to Pain with Anhidrosis. Her top areas of expertise are Silent Thyroiditis, Sitosterolemia, Hypertension, and Glucocorticoid-Remediable Aldosteronism.

Dr. Robin E. Thompson
Internal Medicine
Dr. Robin E. Thompson
Internal Medicine
200 West Carver St, 
Huntington, NY 
 (4.8 mi)
631-421-0020
Languages Spoken:
English
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Robin Thompson is an Internal Medicine provider in Huntington, New York. Dr. Thompson and is rated as an Experienced provider by MediFind in the treatment of Congenital Insensitivity to Pain with Anhidrosis. Her top areas of expertise are Familial Porencephaly, Choroid Plexus Cyst, Arachnoid Cysts, and Obesity.

 
 
 
 
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Dr. Jennifer A. Langsdorf
Neurology
Dr. Jennifer A. Langsdorf
Neurology

Weill Medical College Of Cornell

525 E 68th St, Rm F610, 
New York, NY 
 (24.0 mi)
Languages Spoken:
English

Jennifer Langsdorf is a Neurologist in New York, New York. Dr. Langsdorf and is rated as a Distinguished provider by MediFind in the treatment of Congenital Insensitivity to Pain with Anhidrosis. Her top areas of expertise are Chronic Inflammatory Demyelinating Polyneuropathy, Infantile Axonal Neuropathy, Congenital Insensitivity to Pain with Anhidrosis, and Hereditary Sensory and Autonomic Neuropathy Type 2.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center