Evaluating the Retinal and Choroidal Microvasculature and Structure Using Multimodal Retinal and Choroidal Imaging in Neurodegenerative Disease: iMIND Research Study
Who is this study for? Patients with Neurodegenerative Disease
What treatments are being studied? Retinal Imaging
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY
This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus photography to assess the structure and function of the retinal and choroidal microvasculature and structure in persons with mild cognitive impairment (MCI) and Alzheimer's Disease (AD), Parkinson's Disease (PD), or other neurodegenerative disease, diseases as outlined.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• Adults with neurodegenerative disease ((MCI, PD, AD, FTD, DLB, ALS, MS, HD, TBI, concussion, PTSD and other neurodegenerations as well as Down Syndrome)
• Adults without neurodegenerative disease
Locations
United States
North Carolina
Duke University Medical Center
RECRUITING
Durham
Contact Information
Primary
Sharon Fekrat, MD FACS FASRS
imind@duke.edu
919-681-3937
Time Frame
Start Date: 2017-07-20
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 2000
Treatments
Case
Patients with (MCI, PD, AD, FTD, DLB, ALS, MS, HD, TBI, concussion, PTSD and other neurodegenerations as well as Down Syndrome)
Controls
Controls will be recruited from the relatives/attendants of study participants or will be patients themselves and will not have a neurodegenerative disease diagnosis.
Authors
Related Therapeutic Areas
Sponsors
Collaborators: University of Edinburgh in Scotland, Queens University of Belfast United Kingdom, Tan Tock Seng Hospital in Singapore
Leads: Duke University