Eosinophilic Asthma Overview

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Learn About Eosinophilic Asthma

What is the definition of Eosinophilic Asthma?
Eosinophilic asthma is a form of severe asthma that mainly occurs in adults. Asthma is a chronic condition that causes the airways of the lungs to spasm as they constrict, swell, and produce excess mucous. Eosinophilic asthma is characterized by a high level of eosinophils, which are a type of white blood cells that fight infection. While the cause is unknown, the high number of eosinophils may occur on their own or be caused by an allergic reaction, a drug reaction, or a parasitic disease. The eosinophils create inflammation in the airways that triggers asthma symptoms.
What are the symptoms of Eosinophilic Asthma?
Symptoms of eosinophilic asthma may be severe and persistent and include shortness of breath and/or difficulty breathing, coughing, wheezing, constriction of the airways, and chest tightness. Individuals with eosinophilic asthma also often have chronic sinusitis with nasal polyps.
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What are the current treatments for Eosinophilic Asthma?
Treatment for eosinophilic asthma involves traditional asthma therapies, such as oral or inhaled corticosteroids, which are often combined with new targeted biologic therapies, or monoclonal antibodies, such as benralizumab, dupilumab, mepolizumab, reslizumab, or omalizumab.
Who are the top Eosinophilic Asthma Local Doctors?
Dr. Kristen E. Fisher
Pulmonary Medicine
Dr. Kristen E. Fisher
Pulmonary Medicine

Cardio-Pulmonary Associates, LLC

222 S Woods Mill Rd, 310n, 
Chesterfield, MO 
 (4.1 mi)
314-682-3630
Experience:
15+ years
Languages Spoken:
English
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Kristen Fisher is a Pulmonary Medicine provider in Chesterfield, Missouri. Dr. Fisher has been practicing medicine for over 15 years and is rated as an Experienced provider by MediFind in the treatment of Eosinophilic Asthma. Her top areas of expertise are Lung Metastases, Chronic Obstructive Pulmonary Disease (COPD), Lung Nodules, and Pneumonia. Dr. Fisher is currently accepting new patients.

Dr. Bahaa A. Bedair
Pulmonary Medicine
Dr. Bahaa A. Bedair
Pulmonary Medicine

Missouri Baptist Physician Services LLC

3009 N Ballas Rd, Suite 315a, 
Saint Louis, MO 
 (7.2 mi)
314-996-4700
Languages Spoken:
English
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Accepting New Patients
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Bahaa Bedair is a Pulmonary Medicine provider in Saint Louis, Missouri. Dr. Bedair and is rated as an Experienced provider by MediFind in the treatment of Eosinophilic Asthma. His top areas of expertise are Emphysema, Bullae, Pneumonia, Lung Metastases, and Lung Transplant. Dr. Bedair is currently accepting new patients.

 
 
 
 
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Dr. Hamsa N. Subramanian
Allergy and Immunology
Dr. Hamsa N. Subramanian
Allergy and Immunology

Signature Medical Group Inc

12639 Old Tesson Rd, Suite 115, 
Saint Louis, MO 
 (15.3 mi)
314-849-0311
Languages Spoken:
English, Hindi
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Hamsa Subramanian is an Allergy and Immunologist in Saint Louis, Missouri. Dr. Subramanian and is rated as an Advanced provider by MediFind in the treatment of Eosinophilic Asthma. Her top areas of expertise are Common Variable Immune Deficiency, Primary Immunodeficiency (PID), Eosinophilic Asthma, and Hives. Dr. Subramanian is currently accepting new patients.

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What are the latest Eosinophilic Asthma Clinical Trials?
A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Assess the Efficacy, Safety, and Tolerability of Dexpramipexole Administered Orally for 52 Weeks in Participants With Severe Eosinophilic Asthma
A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Assess the Efficacy, Safety, and Tolerability of Dexpramipexole Administered Orally for 52 Weeks in Participants With Severe Eosinophilic Asthma
Enrollment Status: Recruiting
Publish Date: February 26, 2025
Intervention Type: Drug
Study Phase: Phase 3

Summary: This study will assess the efficacy and safety of dexpramipexole as an adjunctive oral therapy in participants with inadequately controlled asthma with an eosinophilic phenotype and a history of asthma exacerbations.

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Efficacy and Safety of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)
Efficacy and Safety of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)
Enrollment Status: Recruiting
Publish Date: February 19, 2025
Intervention Type: Drug
Study Phase: Phase 3

Summary: A study to evaluate the efficacy and safety of benralizumab administered subcutaneously in patients ≥ 6 to \< 18 years of age with severe eosinophilic asthma, including a well-documented history of asthma exacerbations and uncontrolled asthma receiving high-dose inhaled corticosteroid (ICS) plus at least one additional controller medication.

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