Eosinophilic Asthma Overview

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Learn About Eosinophilic Asthma

What is the definition of Eosinophilic Asthma?
Eosinophilic asthma is a form of severe asthma that mainly occurs in adults. Asthma is a chronic condition that causes the airways of the lungs to spasm as they constrict, swell, and produce excess mucous. Eosinophilic asthma is characterized by a high level of eosinophils, which are a type of white blood cells that fight infection. While the cause is unknown, the high number of eosinophils may occur on their own or be caused by an allergic reaction, a drug reaction, or a parasitic disease. The eosinophils create inflammation in the airways that triggers asthma symptoms.
What are the symptoms of Eosinophilic Asthma?
Symptoms of eosinophilic asthma may be severe and persistent and include shortness of breath and/or difficulty breathing, coughing, wheezing, constriction of the airways, and chest tightness. Individuals with eosinophilic asthma also often have chronic sinusitis with nasal polyps.
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What are the current treatments for Eosinophilic Asthma?
Treatment for eosinophilic asthma involves traditional asthma therapies, such as oral or inhaled corticosteroids, which are often combined with new targeted biologic therapies, or monoclonal antibodies, such as benralizumab, dupilumab, mepolizumab, reslizumab, or omalizumab.
Who are the top Eosinophilic Asthma Local Doctors?
Advanced in Eosinophilic Asthma
Dr. Dean M. Kelaita
Family Medicine | Internal Medicine
Advanced in Eosinophilic Asthma
Dr. Dean M. Kelaita
Family Medicine | Internal Medicine

Mark Twain Medical Center

768 Mountain Ranch Rd, 
San Andreas, CA 
 (0.7 mi)
209-754-3521
Languages Spoken:
English

Dean Kelaita is a Family Medicine specialist and an Internal Medicine provider in San Andreas, California. Dr. Kelaita and is rated as an Advanced provider by MediFind in the treatment of Eosinophilic Asthma. His top areas of expertise are Pneumomediastinum, Subcutaneous Emphysema, Familial Hypertension, and Hypertension.

Distinguished in Eosinophilic Asthma
Dr. Shyamsunder Subramanian
Pulmonary Medicine | Intensive Care Medicine
Distinguished in Eosinophilic Asthma
Dr. Shyamsunder Subramanian
Pulmonary Medicine | Intensive Care Medicine

Sutter Valley Medical Foundation

815 Court St, 
Jackson, CA 
 (11.8 mi)
Languages Spoken:
English
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Shyamsunder Subramanian is a Pulmonary Medicine specialist and an Intensive Care Medicine provider in Jackson, California. Dr. Subramanian and is rated as a Distinguished provider by MediFind in the treatment of Eosinophilic Asthma. His top areas of expertise are Lung Metastases, Chronic Obstructive Pulmonary Disease (COPD), Atypical Pneumonia, and Pneumonia.

 
 
 
 
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Bradley E. Chipps
Distinguished in Eosinophilic Asthma
Dr. Bradley E. Chipps
Allergy and Immunology | Pulmonary Medicine
Distinguished in Eosinophilic Asthma
Dr. Bradley E. Chipps
Allergy and Immunology | Pulmonary Medicine

Capital Allergy And Respiratory Disease Center A Med Corp

1451 Secret Ravine Pkwy, Suite 150, 
Roseville, CA 
 (49.7 mi)
916-580-1891
Languages Spoken:
English
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Offers Telehealth

Bradley Chipps is an Allergy and Immunologist and a Pulmonary Medicine provider in Roseville, California. Dr. Chipps and is rated as a Distinguished provider by MediFind in the treatment of Eosinophilic Asthma. His top areas of expertise are Asthma, Eosinophilic Asthma, Chronic Eosinophilic Pneumonia, Simple Pulmonary Eosinophilia, and Endoscopy.

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What are the latest Eosinophilic Asthma Clinical Trials?
A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Assess the Efficacy, Safety, and Tolerability of Dexpramipexole Administered Orally for 52 Weeks in Participants With Severe Eosinophilic Asthma
A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Assess the Efficacy, Safety, and Tolerability of Dexpramipexole Administered Orally for 52 Weeks in Participants With Severe Eosinophilic Asthma
Enrollment Status: Recruiting
Publish Date: February 26, 2025
Intervention Type: Drug
Study Phase: Phase 3

Summary: This study will assess the efficacy and safety of dexpramipexole as an adjunctive oral therapy in participants with inadequately controlled asthma with an eosinophilic phenotype and a history of asthma exacerbations.

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Efficacy and Safety of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)
Efficacy and Safety of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)
Enrollment Status: Recruiting
Publish Date: February 19, 2025
Intervention Type: Drug
Study Phase: Phase 3

Summary: A study to evaluate the efficacy and safety of benralizumab administered subcutaneously in patients ≥ 6 to \< 18 years of age with severe eosinophilic asthma, including a well-documented history of asthma exacerbations and uncontrolled asthma receiving high-dose inhaled corticosteroid (ICS) plus at least one additional controller medication.

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