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Learn About Familial Pancreatic Cancer

View Main Condition: Pancreatic Cancer

What is the definition of Familial Pancreatic Cancer?
Familial pancreatic cancer (FPC) is the occurrence of pancreatic cancer in two or more first-degree relatives (parent and child, or two siblings). It is sometimes referred to as FPC only when there is not a known hereditary cancer syndrome in an affected family. In 60% of cases it occurs within the head of the pancreas. Symptoms of pancreatic cancer are generally non-specific and may include pain in the upper abdomen that radiates to the back; loss of appetite; significant weight loss; and jaundice due to bile duct obstruction. Pancreatic cancer often goes undetected until the advanced stages of the disease, and rapid tumor growth and metastasis are common. A specific genetic cause of FPC (in the absence of a known syndrome) has not been identified. Familial cases of pancreatic cancer due to hereditary conditions may be caused by genetic changes in any of several genes. Individuals who carry a genetic change in one of these genes are often at an increased risk of other types of cancers as well. In many cases, inheritance of a predisposition to develop FPC is autosomal dominant. In some cases, is may be multifactorial.
What are the alternative names for Familial Pancreatic Cancer?
  • Familial pancreatic cancer
  • Familial pancreatic carcinoma
  • Hereditary pancreatic cancer
  • Hereditary pancreatic carcinoma
Who are the top Familial Pancreatic Cancer Local Doctors?
Michael G. Goggins
Elite in Familial Pancreatic Cancer
Gastroenterology
Elite in Familial Pancreatic Cancer
Gastroenterology

Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville

2360 West Joppa Road, Joppa Concourse STE 205, Joppa Concourse STE 205, 
Lutherville, MD 
Languages Spoken:
English
Offers Telehealth

Dr. Michael G. Goggins is a professor of pathology, medicine and oncology at the Johns Hopkins University School of Medicine. He serves as director of the Pancreatic Cancer Early Detection Laboratory and is an attending physician in medicine in the Division of Gastroenterology and Hepatology at The Johns Hopkins Hospital. He is the Sol Goldman Professor of Pancreatic Cancer Research. Dr. Goggins’ research interests include developing tests to improve the early detection in pancreas cancer, evaluating outcomes of pancreatic surveillance and identifying gene variants responsible for inherited susceptibility to pancreatic cancer. He obtained his medical degree in 1988 from Trinity College of the University of Dublin, Ireland. He completed a residency in internal medicine and a fellowship in Gastroenterology at St. James' Hospital in Dublin. He obtained his Membership of the Royal College of Physicians of Ireland in 1991 and his European Diploma in Gastroenterology in 1995. He joined the Johns Hopkins faculty in 1999. Dr. Goggins is a member of the Royal College of Physicians of Ireland. He sits on the editorial boards of Gut. Dr. Goggins is rated as an Elite provider by MediFind in the treatment of Familial Pancreatic Cancer. His top areas of expertise are Familial Pancreatic Cancer, Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma, Pancreatectomy, and Pancreaticoduodenectomy.

Detlef K. Bartsch
Elite in Familial Pancreatic Cancer
Elite in Familial Pancreatic Cancer
Marburg An Der Lahn, HE, DE 

Detlef Bartsch practices in Marburg An Der Lahn, Germany. Bartsch is rated as an Elite expert by MediFind in the treatment of Familial Pancreatic Cancer. Their top areas of expertise are Familial Pancreatic Cancer, Pancreatic Cancer, Multiple Endocrine Neoplasia Type 1, Parathyroidectomy, and Pancreaticoduodenectomy.

 
 
 
 
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Charles J. Yeo
Elite in Familial Pancreatic Cancer
General Surgery | Oncology
Elite in Familial Pancreatic Cancer
General Surgery | Oncology

Jefferson Surgery - Honickman Center

1101 Chestnut Street, Floor 8, 
Philadelphia, PA 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Charles Yeo is an Oncologist and a General Surgeon in Philadelphia, Pennsylvania. Dr. Yeo is rated as an Elite provider by MediFind in the treatment of Familial Pancreatic Cancer. His top areas of expertise are Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma, Familial Pancreatic Cancer, Pancreaticoduodenectomy, and Pancreatectomy. Dr. Yeo is currently accepting new patients.

What are the latest Familial Pancreatic Cancer Clinical Trials?
Familial Investigations of Childhood Cancer Predisposition

Summary: NOTE: This is a research study and is not meant to be a substitute for clinical genetic testing. Families may never receive results from the study or may receive results many years from the time they enroll. If you are interested in clinical testing please consider seeing a local genetic counselor or other genetics professional. If you have already had clinical genetic testing and meet eligibility...

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IMAGINE: IMproving Access to Genetic INformation for Everyone - A Prospective Trial of a Linguistically and Culturally Appropriate Mainstreaming Model for Hereditary Cancer Multigene Panel Testing Among Diverse Cancer Patients

Summary: Genetic testing is a type of test that detects changes to the genes-the DNA instructions that are passed on from the mother and father. The results of a genetic test can confirm whether the participant has a genetic disorder, which is a disease caused in whole or in part by changes to the genes. Genetic testing can also help determine a person's chance of getting or passing on a genetic disorder. ...

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center