Fascioliasis Overview

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Learn About Fascioliasis

What is the definition of Fascioliasis?
Fascioliasis is a rare foodborne parasitic animal infection that can be transmitted to humans that is usually caused by Fasciola hepatica (flatworms), also known as “common liver fluke," or the parasite, Fasciola gigantica. Individuals are infected by eating raw watercress or other water plants contaminated with the parasite larvae, after which the larvae mature and move through the intestines to the liver and bile ducts and produce eggs. The parasites can also migrate to other areas of the body. A subtype of fascioliasis, known as Halzoun syndrome, may affect the throat.
What are the symptoms of Fascioliasis?
Fascioliasis has both early (acute) and late (chronic) phases. During the acute phase (two to four months) when the parasites migrate from the intestines to the liver, symptoms may include nausea and vomiting, gastrointestinal problems, extreme abdominal pain and/or tenderness, swollen liver, internal bleeding, fever, rash, hives, difficulty breathing, and bronchial asthma attacks. During the chronic phase when the parasites settle into the bile ducts, patients may experience similar symptoms of the acute phase, along with intermittent pain, intolerance to fatty food, itching, bile duct inflammation, blockage and inflammation of the gallbladder, gallstones, pancreas (pancreatitis), liver fibrosis, jaundice (yellowing of skin and eyes), and anemia.
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What are the current treatments for Fascioliasis?
Treatment for fascioliasis with the preferred drug, oral triclabendazole, should be administered promptly to prevent liver complications and usually provides a cure.
Who are the top Fascioliasis Local Doctors?
Christopher R. Shubert
Experienced in Fascioliasis
Dr. Christopher R. Shubert
Surgical Oncology | General Surgery
Experienced in Fascioliasis
Dr. Christopher R. Shubert
Surgical Oncology | General Surgery

Johns Hopkins University

600 N Wolfe St, Blalock 266, 
Baltimore, MD 
 (7.5 mi)
410-502-4340
Languages Spoken:
English
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Offers Telehealth

Christopher Shubert is a General Surgeon in Baltimore, Maryland. Dr. Shubert and is rated as an Experienced provider by MediFind in the treatment of Fascioliasis. His top areas of expertise are Pancreatic Cancer, Cholangiocarcinoma (Bile Duct Cancer), Familial Pancreatic Cancer, Pancreaticoduodenectomy, and Pancreatectomy.

Experienced in Fascioliasis
Dr. Nathan A. Scott
Internal Medicine
Experienced in Fascioliasis
Dr. Nathan A. Scott
Internal Medicine
1235 E Monument St, 
Baltimore, MD 
 (7.0 mi)
410-327-5100
Languages Spoken:
English

Nathan Scott is an Internal Medicine provider in Baltimore, Maryland. Dr. Scott and is rated as an Experienced provider by MediFind in the treatment of Fascioliasis. His top areas of expertise are Glucocorticoid-Remediable Aldosteronism, Familial Hypertension, Hypertension, and Fascioliasis.

 
 
 
 
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Experienced in Fascioliasis
Dr. Thomas A. Traill
Cardiology
Experienced in Fascioliasis
Dr. Thomas A. Traill
Cardiology
600 N Wolfe St, 
Baltimore, MD 
 (7.5 mi)
410-955-3116
Languages Spoken:
English
See accepted insurances

Thomas Traill is a Cardiologist in Baltimore, Maryland. Dr. Traill and is rated as an Experienced provider by MediFind in the treatment of Fascioliasis. His top areas of expertise are Bicuspid Aortic Valve, Marfan Syndrome, Arachnodactyly, and Congenital Contractural Arachnodactyly.

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What are the latest Fascioliasis Clinical Trials?
A Phase IV, Multi-center, Open-label Study to Determine the Safety, Tolerability and Clinical Outcomes Following Oral Administration of EGATEN™ (Triclabendazole) in Patients (6 Years of Age or Older) With Fascioliasis.
A Phase IV, Multi-center, Open-label Study to Determine the Safety, Tolerability and Clinical Outcomes Following Oral Administration of EGATEN™ (Triclabendazole) in Patients (6 Years of Age or Older) With Fascioliasis.
Who is this study for: Patients 6 years of age or older with fascioliasis
Enrollment Status: Recruiting
Publish Date: December 31, 2024
Intervention Type: Drug
Study Drug: Egaten
Study Phase: Phase 4

Summary: This is a multicenter, open label, non-comparative, single arm multi-country study in approximately 300 adult and pediatric subjects (≥ 6 years of age) with fascioliasis. The study population consists of male and female adult and pediatric patients (≥ 6 years of age). The study will enroll approximately 300 subjects with acute (minimum 15% of overall study population) or chronic fascioliasis. Enro...

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