Learn About Frasier Syndrome
Frasier syndrome is a condition that affects the kidneys and genitalia.
Mutations in the WT1 gene cause Frasier syndrome. The WT1 gene provides instructions for making a protein that regulates the activity of other genes by attaching (binding) to specific regions of DNA. On the basis of this action, the WT1 protein is called a transcription factor. The WT1 protein plays a role in the development of the kidneys and gonads (ovaries in females and testes in males) before birth.
Frasier syndrome is thought to be a rare condition; approximately 50 cases have been described in the scientific literature.
This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder.
Associates In Nephrology, SC
Chirag Patel is a Nephrologist in Park Ridge, Illinois. Dr. Patel is rated as a Distinguished provider by MediFind in the treatment of Frasier Syndrome. His top areas of expertise are Acute Kidney Failure, Nephrosclerosis, Renovascular Hypertension, and End-Stage Renal Disease (ESRD).
Atrium Health Levine Children's Nephrology
Donald Weaver is a Pediatric Nephrologist in Charlotte, North Carolina. Dr. Weaver is rated as an Experienced provider by MediFind in the treatment of Frasier Syndrome. His top areas of expertise are Posterior Urethral Valves, Nephrotic Syndrome, CHARGE Syndrome, Koolen De Vries Syndrome, and Kidney Transplant. Dr. Weaver is currently accepting new patients.
Balboa Nephrology Medical Group Inc
Guy Lund is a Nephrologist in San Diego, California. Dr. Lund is rated as a Distinguished provider by MediFind in the treatment of Frasier Syndrome. His top areas of expertise are Poststreptococcal Glomerulonephritis, Autosomal Dominant Polycystic Kidney Disease, Diffuse Mesangial Sclerosis, and Frasier Syndrome.
Summary: CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures for rare diseases. The CoRDS team works with patient advocacy groups, in...
Published Date: March 01, 2013
Published By: National Institutes of Health