Gliosarcoma Overview

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Learn About Gliosarcoma

View Main Condition: Brain Tumor

What is the definition of Gliosarcoma?
Gliosarcoma is a rare type of brain tumor that develops from glial cells, which are specialized cells that surround and support neurons (nerve cells). Unlike gliomas, gliosarcomas have a higher likelihood to spread to the lymph nodes, lungs, and liver. 
What are the causes of Gliosarcoma?
The cause of gliosarcomas is still unknown. However, gliosarcomas generally tend to be more common in adults than children. Men are also more likely to develop gliosarcomas than women.
What are the symptoms of Gliosarcoma?
The symptoms of gliosarcomas primarily depend on the tumor's location as well as how much the tumor has spread. Common symptoms include headaches, memory difficulties, fatigue, numbness, balance issues, and seizures. 
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What are the current treatments for Gliosarcoma?
Treatment for gliosarcoma may include surgery, radiation therapy, and/or chemotherapy. Surgery to remove as much of the tumor as possible is generally the first step in treating gliosarcoma. However, if a tumor is located near a sensitive area in the brain, surgery may not be possible at all. Radiation therapy often follows surgery for the treatment of gliosarcoma. Radiation therapy involves the use of high-energy beams, including X-rays or protons, to destroy tumor cells. Chemotherapy involves the use of drugs, either taken orally or injected through a vein, to kill tumor cells. Chemotherapy is often used in combination with radiation therapy.
Who are the top Gliosarcoma Local Doctors?
Experienced in Gliosarcoma
Dr. Lisa S. Wang
Hematology Oncology | Hematology | Oncology
Experienced in Gliosarcoma
Dr. Lisa S. Wang
Hematology Oncology | Hematology | Oncology

Pih Health Physicians

12462 Putnam St, Suite 203, 
Whittier, CA 
 (1.0 mi)
562-789-5430
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Lisa Wang is a Hematologist Oncology specialist and a Hematologist in Whittier, California. Dr. Wang and is rated as an Experienced provider by MediFind in the treatment of Gliosarcoma. Her top areas of expertise are Paget Disease of the Breast, Inflammatory Breast Cancer, Angiosarcoma, and Childhood Iron Deficiency Anemia.

Experienced in Gliosarcoma
Dr. Jeremy Y. Chuang
Hematology Oncology | Hematology | Oncology
Experienced in Gliosarcoma
Dr. Jeremy Y. Chuang
Hematology Oncology | Hematology | Oncology

Pih Health Physicians

12462 Putnam St, 
Whittier, CA 
 (1.0 mi)
562-789-5430
Experience:
9+ years
Languages Spoken:
English
Offers Telehealth

Jeremy Chuang is a Hematologist Oncology specialist and a Hematologist in Whittier, California. Dr. Chuang has been practicing medicine for over 9 years and is rated as an Experienced provider by MediFind in the treatment of Gliosarcoma. His top areas of expertise are Appendix Cancer, Colorectal Cancer, Disseminated Intravascular Coagulation, and Stomach Cancer.

 
 
 
 
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Experienced in Gliosarcoma
Dr. Leo E. Orr
Hematology Oncology | Hematology | Oncology
Experienced in Gliosarcoma
Dr. Leo E. Orr
Hematology Oncology | Hematology | Oncology

The Oncology Institute Ca, A Professional Corporation

101 E Beverly Blvd, Suite 200, 
Montebello, CA 
 (4.5 mi)
323-278-4400
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Leo Orr is a Hematologist Oncology specialist and a Hematologist in Montebello, California. Dr. Orr and is rated as an Experienced provider by MediFind in the treatment of Gliosarcoma. His top areas of expertise are Paget Disease of the Breast, Malignant Mixed Mullerian Tumor, Breast Cancer, and Endometrial Cancer.

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How do I prevent Gliosarcoma?
There is no known way to prevent gliosarcomas. However, if you develop any symptoms common to a gliosarcoma, it is recommended to make an appointment with your doctor to be properly diagnosed.
What are the latest Gliosarcoma Clinical Trials?
A Phase I Clinical Trial With a Window-of-Opportunity Component of Engineered NK Cells Containing Deleted TGF-ßR2 and NR3C1 in Recurrent Glioblastoma
A Phase I Clinical Trial With a Window-of-Opportunity Component of Engineered NK Cells Containing Deleted TGF-ßR2 and NR3C1 in Recurrent Glioblastoma
Who is this study for: Patients with recurrent glioblastoma
Enrollment Status: Recruiting
Publish Date: February 20, 2025
Intervention Type: Procedure, Biological
Study Drug: Cord Blood-derived Expanded Allogeneic Natural Killer Cells
Study Phase: Phase 1

Summary: This phase I trial is to find out the best dose, possible benefits and/or side effects of engineered natural killer (NK) cells containing deleted TGF-betaR2 and NR3C1 (cord blood \[CB\]-NK-TGF-betaR2-/NR3C1-) in treating patients with glioblastoma that has come back (recurrent). CB-NK-TGF-betaR2-/NR3C1- cells are genetically changed immune cells that may help to control the disease.

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A First-in-human Phase I Single-agent Dose-escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
A First-in-human Phase I Single-agent Dose-escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
Who is this study for: Patients with recurrent and rare primary central nervous system neoplasms
Enrollment Status: Recruiting
Publish Date: February 07, 2025
Intervention Type: Drug
Study Drug: ONC206
Study Phase: Phase 1

Summary: The primary objective of this Phase 1, open-label, dose-escalation, and exploratory study is to evaluate the safety and tolerability profile (establish the maximum-tolerated dose) and evaluate the occurrence of dose-limiting toxicities (DLTs) following single weekly or multiple-day weekly dose regimens of single-agent, oral ONC206 in patients with recurrent, primary central nervous system (CNS) ne...

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What are some Advocacy Organizations?
keep-punching-brain-cancer

Keep Punching supports patients, healthcare providers, and researchers in their fight to prevent and eradicate brain cancer and minimize treatment-related side effects that may adversely impact function and comfort.