Hypereosinophilic Syndrome Overview

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Learn About Hypereosinophilic Syndrome

What is the definition of Hypereosinophilic Syndrome?
Hypereosinophilic syndrome (HES) refers to a rare group of conditions that are associated with persistent eosinophilia with evidence of organ involvement. Signs and symptoms vary significantly based on which parts of the body are affected. Although any organ system can be involved in HES, the heart, central nervous system, skin, and respiratory tract are the most commonly affected. The condition was originally thought to be "idiopathic" or of unknown cause. However, recent advances in diagnostic testing have allowed a cause to be identified in approximately a quarter of cases.
What are the alternative names for Hypereosinophilic Syndrome?
  • Hypereosinophilic syndrome
  • HES
  • Hypereosinophilic syndrome, idiopathic
Who are the top Hypereosinophilic Syndrome Local Doctors?
Praveen Akuthota
Elite in Hypereosinophilic Syndrome
Dr. Praveen Akuthota
Intensive Care Medicine | Pulmonary Medicine
Elite in Hypereosinophilic Syndrome
Dr. Praveen Akuthota
Intensive Care Medicine | Pulmonary Medicine

Regents Of The University Of California

200 W Arbor Dr, 
San Diego, CA 
858-249-6753
Languages Spoken:
English
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Offers Telehealth

Praveen Akuthota is an Intensive Care Medicine specialist and a Pulmonary Medicine provider in San Diego, California. Dr. Akuthota is rated as an Elite provider by MediFind in the treatment of Hypereosinophilic Syndrome. His top areas of expertise are Hypereosinophilic Syndrome, Eosinophilic Granulomatosis with Polyangiitis (EGPA, Churg-Strauss Syndrome), Asthma, Eosinophilic Asthma, and Gastrostomy.

Elite in Hypereosinophilic Syndrome
Dr. Michael Wechsler
Cardiology | Pulmonary Medicine
Elite in Hypereosinophilic Syndrome
Dr. Michael Wechsler
Cardiology | Pulmonary Medicine

Office

1400 Jackson St Ste A542, 
Denver, CO 
303-398-4461
Experience:
33+ years
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Michael Wechsler is a Cardiologist and a Pulmonary Medicine provider in Denver, Colorado. Dr. Wechsler has been practicing medicine for over 33 years and is rated as an Elite provider by MediFind in the treatment of Hypereosinophilic Syndrome. His top areas of expertise are Asthma, Eosinophilic Granulomatosis with Polyangiitis (EGPA, Churg-Strauss Syndrome), Hypereosinophilic Syndrome, and Eosinophilic Asthma.

 
 
 
 
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Ian D. Pavord
Elite in Hypereosinophilic Syndrome
Ian D. Pavord
Elite in Hypereosinophilic Syndrome
Ian D. Pavord
Oxford, ENG, GB 

Ian Pavord practices in Oxford, United Kingdom. Mr. Pavord is rated as an Elite expert by MediFind in the treatment of Hypereosinophilic Syndrome. His top areas of expertise are Eosinophilic Asthma, Asthma, Chronic Obstructive Pulmonary Disease (COPD), and Chronic Cough.

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What are the latest Hypereosinophilic Syndrome Clinical Trials?
The Safety and Efficay Investigation of IL-5 CAR-T Cell Therapy for Patients With Refractory/Relapsed Eosinophilic Leukemia
The Safety and Efficay Investigation of IL-5 CAR-T Cell Therapy for Patients With Refractory/Relapsed Eosinophilic Leukemia
Enrollment Status: Recruiting
Publish Date: December 10, 2025
Intervention Type: Drug
Study Phase: Phase 1

Summary: This is an open-label, single-arm clinical study designed to evaluate the efficacy and safety of IL-5 CAR-T cell therapy in the treatment of patients with CD125-positive eosinophilic leukemia.

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The Use of Machine Learning Techniques for the Differential Diagnosis Between Eosinophilic Granulomatosis With Polyangiitis and Hypereosinophilic Syndrome
The Use of Machine Learning Techniques for the Differential Diagnosis Between Eosinophilic Granulomatosis With Polyangiitis and Hypereosinophilic Syndrome
Enrollment Status: Recruiting
Publish Date: December 10, 2025
Intervention Type: Procedure
Study Phase: Not Applicable

Summary: The purpose of this study is to collect clinical, laboratory, and instrumental data from patients with eosinophilic granulomatosis with polyangiitis or hypereosinophilic syndrome, which will then be analyzed using artificial intelligence techniques with the aim of identifying characteristics that differentiate the two diseases and can predict the response to the treatment plan.

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center