Invertebral Disc Disease Overview

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Learn About Invertebral Disc Disease

What is the definition of Invertebral Disc Disease?
Intervertebral disc disease, also known as degenerative disc disease, is a condition in which the one or more of the discs that cushion and absorb pressure between the vertebrae of the spine degenerate and cause pain. Intervertebral disc disease may lead to curvature of the spine (adult scoliosis), herniated disc, spinal stenosis (narrowing), and slipped discs (spondylolisthesis). Intervertebral disc disease is a part of aging and is common in older adults.
What are the symptoms of Invertebral Disc Disease?
Symptoms of intervertebral disc disease depend on the type and affected discs. The most common symptom of intervertebral disc disease is periodic or chronic pain in the neck or back. The pain may increase when bending, twisting the body, sitting, or lifting. Herniated intervertebral discs can press on the spinal nerves and cause pain that runs down the leg (sciatica), weakness, and numbness in the back or legs. Degenerated intervertebral discs may also cause the growth of bone spurs (osteophytes) at their edges that pinch the spinal nerves, causing weakness, numbness, difficulty walking, and bladder and bowel control problems. A completely degenerated intervertebral disc may cause permanent nerve damage and impaired movement.
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What are the current treatments for Invertebral Disc Disease?
Treatment for intervertebral disc disease includes medications, such as acetaminophen or non-steroidal anti-inflammatory drugs; arthritis medications; hot and cold therapy; stretching; physical therapy; exercise; oral cortisone; cortisone injections; radiofrequency neurotomy; or spinal decompression surgery, such as discectomy, foraminotomy, laminectomy, bone spur (osteophyte) removal; and spinal fusion.
Who are the top Invertebral Disc Disease Local Doctors?
Ira D. Fisch
Distinguished in Invertebral Disc Disease
Dr. Ira D. Fisch
Orthopedics
Distinguished in Invertebral Disc Disease
Dr. Ira D. Fisch
Orthopedics

Aligned Orthopedic Partners

10215 Fernwood Road, Suite 506, 
Bethesda, MD 
301-530-1010
Languages Spoken:
English
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Offers Telehealth

Ira Fisch is an Orthopedics provider in Bethesda, Maryland. Dr. Fisch is rated as a Distinguished provider by MediFind in the treatment of Invertebral Disc Disease. His top areas of expertise are Sciatica, Invertebral Disc Disease, Diffuse Idiopathic Skeletal Hyperostosis, Microdiscectomy, and Cervical Disc Surgery.

Nicholas J. Wills
Distinguished in Invertebral Disc Disease
Dr. Nicholas J. Wills
Orthopedics
Distinguished in Invertebral Disc Disease
Dr. Nicholas J. Wills
Orthopedics

Summit Orthopedics

2620 Eagan Woods Drive, Floor 1, 
Eagan, MN 
651-968-5201
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Nicholas Wills, M.D., is a spine surgeon at Summit Orthopedics, serving Minneapolis and St. Paul metro patients. He specializes in minimally invasive spine surgery, total disc replacement, as well as cervical, thoracic, and lumbar spine conditions. Across the nation, Dr. Wills trains other surgeons on the best techniques for disc replacement surgery. He was a pioneer in this market, adopting new technology that allows for a two-level disc replacement that maintains the motion at both levels of repair. His surgical expertise has won him repeated recognition on the Mpls.St.Paul Magazine’s Rising Stars list. Dr. Wills is rated as a Distinguished provider by MediFind in the treatment of Invertebral Disc Disease. His top areas of expertise are Spinal Stenosis, Invertebral Disc Disease, Spondylolisthesis, Herniated Disc Surgery, and Cervical Disc Surgery.

 
 
 
 
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Laura S. Stone
Elite in Invertebral Disc Disease
Laura S. Stone
Elite in Invertebral Disc Disease
Laura S. Stone
3610 University Street, 
Montreal, QC, CA 

Laura Stone practices in Montreal, Canada. Ms. Stone is rated as an Elite expert by MediFind in the treatment of Invertebral Disc Disease. Her top areas of expertise are Invertebral Disc Disease, Chronic Pain, Neuralgia, Spinal Fusion, and Oophorectomy.

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What are the latest Invertebral Disc Disease Clinical Trials?
A Prospective, Randomized, Double-Blinded, Sham-Controlled, Multicenter Study to Evaluate the Safety and Efficacy of IDCT in Subjects With Single-Level, Symptomatic Mild to Moderate Lumbar Intervertebral Disc Degeneration
A Prospective, Randomized, Double-Blinded, Sham-Controlled, Multicenter Study to Evaluate the Safety and Efficacy of IDCT in Subjects With Single-Level, Symptomatic Mild to Moderate Lumbar Intervertebral Disc Degeneration
Enrollment Status: Recruiting
Publish Date: December 03, 2025
Intervention Type: Biological, Other
Study Phase: Phase 3

Summary: This is a Phase III, randomized, double-blinded, Sham-controlled, multi-center study in subjects with single-level, symptomatic lumbar (L3- S1) intervertebral disc degeneration. The study will have a 52-week primary period followed by 52 week Follow-up Period (total of 104 weeks). The study protocol will be approved by the Institutional Review Board (IRB) or Independent Ethics Committee (IEC), and...

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A Prospective, Randomized, Multi-center Study to Assess the Performance of MagnEtOs Flex Matrix Mixed With Local Autograft Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented poSterolatEral Lumbar/Thoraco-lumbar Fusion (PLF)
A Prospective, Randomized, Multi-center Study to Assess the Performance of MagnEtOs Flex Matrix Mixed With Local Autograft Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented poSterolatEral Lumbar/Thoraco-lumbar Fusion (PLF)
Enrollment Status: Recruiting
Publish Date: December 02, 2025
Intervention Type: Device
Study Phase: Not Applicable

Summary: This is a phase IV post-marketing study for MagnetOs Flex Matrix. MagnetOs Flex Matrix is a synthetic bone graft extender product that is routinely used by surgeons as a treatment for patients with degenerative disc disease and undergoing spinal fusion surgery. In this study, MagnetOs Flex Matrix will be used according to the latest U.S. Instructions For Use, specifically as a bone graft extender ...

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