Juvenile Paget's Disease Overview
Learn About Juvenile Paget's Disease
Juvenile Paget disease is a disorder that affects bone growth. This disease causes bones to be abnormally large, misshapen, and easily broken (fractured).
Juvenile Paget disease is caused by mutations in the TNFRSF11B gene. This gene provides instructions for making a protein that is involved in bone remodeling, a normal process in which old bone is broken down and new bone is created to replace it.
Juvenile Paget disease is rare; about 50 affected individuals have been identified worldwide.
This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.
The Medical College Of Wisconsin Inc
Emily Joachim is a Nephrologist in Milwaukee, Wisconsin. Dr. Joachim and is rated as an Experienced provider by MediFind in the treatment of Juvenile Paget's Disease. Her top areas of expertise are Childhood Hypophosphatasia (HPP), Hypophosphatasia (HPP), Juvenile Paget's Disease, Hypophosphatemia, and Kidney Transplant. Dr. Joachim is currently accepting new patients.
Froedtert Andthe Medical College Of Wisconsin Community Physicians Inc
David Pryba is an Internal Medicine provider in Wauwatosa, Wisconsin. Dr. Pryba and is rated as an Experienced provider by MediFind in the treatment of Juvenile Paget's Disease. His top areas of expertise are Osteopenia, Melorheostosis, Melorheostosis with Osteopoikilosis, and Zollinger-Ellison Syndrome. Dr. Pryba is currently accepting new patients.
The Medical College Of Wisconsin Inc
Barbara Bresnahan is a Nephrologist in Milwaukee, Wisconsin. Dr. Bresnahan and is rated as an Advanced provider by MediFind in the treatment of Juvenile Paget's Disease. His top areas of expertise are IgA Nephropathy, Thin Basement Membrane Nephropathy, Nephrosclerosis, Renovascular Hypertension, and Kidney Transplant. Dr. Bresnahan is currently accepting new patients.
Published Date: February 01, 2010
Published By: National Institutes of Health