Learn About Lacrimo-Auriculo-Dento-Digital Syndrome
Lacrimo-auriculo-dento-digital (LADD) syndrome is a genetic disorder that mainly affects the eyes, ears, mouth, and hands. LADD syndrome is characterized by defects in the tear-producing lacrimal system (lacrimo-), ear problems (auriculo-), dental abnormalities (dento-), and deformities of the fingers (digital).
Mutations in the FGFR2, FGFR3, or FGF10 gene can cause LADD syndrome.
LADD syndrome appears to be a rare condition; at least 60 cases have been described in the scientific literature.
This condition is inherited in an autosomal dominant pattern, which means a mutation in one copy of the FGFR2, FGFR3, or FGF10 gene in each cell is sufficient to cause the disorder.
Matthias Griese practices in Munich, Germany. Mr. Griese is rated as an Elite expert by MediFind in the treatment of Lacrimo-Auriculo-Dento-Digital Syndrome. His top areas of expertise are Pulmonary Alveolar Proteinosis, Lacrimo-Auriculo-Dento-Digital Syndrome, Acute Interstitial Pneumonia, Interstitial Lung Disease, and Lung Transplant.
Nicolaus Schwerk practices in Hannover, Germany. Mr. Schwerk is rated as an Elite expert by MediFind in the treatment of Lacrimo-Auriculo-Dento-Digital Syndrome. His top areas of expertise are Lacrimo-Auriculo-Dento-Digital Syndrome, Interstitial Lung Disease, Acute Interstitial Pneumonia, Lung Transplant, and Endoscopy.
Katharina Schutz practices in Hannover, Germany. Ms. Schutz is rated as an Elite expert by MediFind in the treatment of Lacrimo-Auriculo-Dento-Digital Syndrome. Her top areas of expertise are Lacrimo-Auriculo-Dento-Digital Syndrome, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Infantile Pneumothorax, and Lung Transplant.
Published Date: June 01, 2013
Published By: National Institutes of Health