Learn About Leukemia
Leukemia is a type of blood cancer that begins in the bone marrow. Bone marrow is the soft tissue in the center of the bones, where blood cells are produced.
The term leukemia means white blood. White blood cells (leukocytes) fight infections and other foreign substances. Leukocytes are made in the bone marrow.
Leukemia leads to an uncontrolled increase in the number of white blood cells.
The cancerous cells prevent healthy red cells, platelets, and mature white cells (leukocytes) from being made. Life-threatening symptoms can then develop as normal blood cells decline.
The cancer cells can spread to the bloodstream and lymph nodes. They can also travel to the brain and spinal cord (the central nervous system) and other parts of the body.
Leukemia can affect children and adults.
Leukemias are divided into two major types:
- Acute (which progresses quickly)
- Chronic (which progresses more slowly)
The main types of leukemia are:
- Acute lymphocytic leukemia (ALL)
- Acute myeloid leukemia (AML)
- Chronic lymphocytic leukemia (CLL)
- Chronic myeloid leukemia (CML)
Tri-County Hematology And Oncology Associates Inc
Nagaprasad Nagajothi is a Hematologist Oncology specialist and a Hematologist in Massillon, Ohio. Dr. Nagajothi and is rated as an Experienced provider by MediFind in the treatment of Leukemia. His top areas of expertise are Large-Cell Immunoblastic Lymphoma, Anemia, Familial Colorectal Cancer, Pleuropulmonary Blastoma, and Bone Marrow Aspiration. Dr. Nagajothi is currently accepting new patients.
Skill Doc 101 LLC
Brian Mcclain is an Internal Medicine provider in Canton, Ohio. Dr. Mcclain and is rated as an Experienced provider by MediFind in the treatment of Leukemia. His top areas of expertise are Alzheimer's Disease, Dementia, Idiopathic Edema, and Anemia.
Aultman Cancer Care LLC
Sunitha Vemulapalli is a Hematologist Oncology specialist and a Hematologist in Canton, Ohio. Dr. Vemulapalli and is rated as an Experienced provider by MediFind in the treatment of Leukemia. Her top areas of expertise are Lung Cancer, Thrombocytopenia, Paget Disease of the Breast, Childhood Iron Deficiency Anemia, and Bone Marrow Aspiration. Dr. Vemulapalli is currently accepting new patients.
Common conditions include: Acute Erythroid Leukemia (AEL), Acute Lymphoblastic Leukemia (ALL), Acute Megakaryoblastic Leukemia, Acute Monoblastic Leukemia (AmoL)
Summary: This phase II trial compares the combination of inotuzumab ozogamicin and chemotherapy to the usual chemotherapy in treating patients with B-cell acute lymphoblastic leukemia or B-cell lymphoblastic lymphoma. Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a drug, called CalichDMH. Inotuzumab is a form of targeted therapy because it attaches to specific molecules (rece...
Summary: This phase II MyeloMATCH treatment trial compares cytarabine with daunorubicin versus cytarabine with daunorubicin and venetoclax versus venetoclax with azacitidine for the treatment of younger patients with intermediate risk acute myeloid leukemia (AML). Cytarabine is a drug that inhibits some of the enzymes needed for deoxyribonucleic acid (DNA) replication and repair and can slow or stop the gr...
Published Date: March 31, 2024
Published By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Appelbaum FR. Acute leukemias in adults. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 95.
Brown JR. Chronic lymphocytic leukemia. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 169.
Hunger SP, Teachey DT, Grupp S, Aplenc R. Childhood leukemia. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 93.
Radich J. Chronic myeloid leukemia. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 170.
Walter RB, Appelbaum FA. The acute leukemias. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 168.