Liposarcoma Overview

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Learn About Liposarcoma

What is the definition of Liposarcoma?
A liposarcoma, also called soft tissue sarcoma, is a rare type of cancerous tumor that grows in the fat cells of the body. Liposarcomas occur most often on the abdomen, arms, thighs, and legs. There are several different types of liposarcomas.
What are the symptoms of Liposarcoma?
Symptoms of liposarcoma depend on where the tumor appears. Symptoms of liposarcoma can include a lump under the skin that continues to grow; pain, swelling, or numbness around the lump; weakness in the affected limb; abdominal pain; abdominal swelling; abdominal fullness after eating; constipation; black or tarry stool; vomiting blood; fever; chills; fatigue; night sweats; and weight loss.
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What are the current treatments for Liposarcoma?
Treatment for liposarcoma depends on the type, size, and location of the tumor. Treatments for liposarcoma include surgery, radiation therapy, and chemotherapy. Newer types of chemotherapy for the treatment of liposarcoma include erybulin mesylate and trabectedin.
Who are the top Liposarcoma Local Doctors?
Experienced in Liposarcoma
Dr. Caleb R. Dulaney
Radiation Oncology
Experienced in Liposarcoma
Dr. Caleb R. Dulaney
Radiation Oncology

Anderson Regional Medical Center

1704 23rd Ave, 
Meridian, MS 
 (0.7 mi)
601-485-5081
Experience:
12+ years
Languages Spoken:
English
Accepting New Patients

Caleb Dulaney is a Radiation Oncologist in Meridian, Mississippi. Dr. Dulaney has been practicing medicine for over 12 years and is rated as an Experienced provider by MediFind in the treatment of Liposarcoma. His top areas of expertise are Prostate Cancer, Breast Cancer, Familial Prostate Cancer, Pleuropulmonary Blastoma, and Prostatectomy. Dr. Dulaney is currently accepting new patients.

Experienced in Liposarcoma
Dr. Matthew W. Cassell
Hematology Oncology | Hematology | Oncology
Experienced in Liposarcoma
Dr. Matthew W. Cassell
Hematology Oncology | Hematology | Oncology

Meridian Oncology Associates

1704 23rd Ave. 2nd Floor, 
Meridian, MS 
 (9.5 mi)
601-482-1555
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Matthew Cassell is a Hematologist Oncology specialist and a Hematologist in Meridian, Mississippi. Dr. Cassell and is rated as an Experienced provider by MediFind in the treatment of Liposarcoma. His top areas of expertise are Familial Colorectal Cancer, Colorectal Cancer, Pleuropulmonary Blastoma, Lung Cancer, and Gastrostomy. Dr. Cassell is currently accepting new patients.

 
 
 
 
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Experienced in Liposarcoma
Dr. Jennifer T. Eubanks
Hematology Oncology | Hematology | Oncology
Experienced in Liposarcoma
Dr. Jennifer T. Eubanks
Hematology Oncology | Hematology | Oncology

Meridian Oncology Associates

1704 23rd Ave. 2nd Floor, 
Meridian, MS 
 (9.5 mi)
601-482-1555
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Jennifer Eubanks is a Hematologist Oncology specialist and a Hematologist in Meridian, Mississippi. Dr. Eubanks and is rated as an Experienced provider by MediFind in the treatment of Liposarcoma. Her top areas of expertise are Pleuropulmonary Blastoma, Lung Cancer, Non-Small Cell Lung Cancer (NSCLC), and EGFR Positive Lung Cancer. Dr. Eubanks is currently accepting new patients.

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What are the latest Liposarcoma Clinical Trials?
A Phase 1 Study of Peposertib (M3814) and Low-Dose Liposomal Doxorubicin (Doxil�) in Patients With Metastatic Leiomyosarcoma and Other Soft Tissue Sarcomas
A Phase 1 Study of Peposertib (M3814) and Low-Dose Liposomal Doxorubicin (Doxil�) in Patients With Metastatic Leiomyosarcoma and Other Soft Tissue Sarcomas
Enrollment Status: Recruiting
Publish Date: February 26, 2025
Intervention Type: Drug, Procedure
Study Phase: Phase 1

Summary: This phase I trial tests the safety, side effects, and best dose of combination therapy with liposomal doxorubicin and peposertib in treating patients with sarcoma that has spread from where it first started, to other places in the body (metastatic), or cannot be removed by surgery (unresectable) and for which no known cure is available (advanced). Doxorubicin is in a class of medications called a...

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A Phase Ib/II Study of APG-115 in Combination With PD-1 Inhibitor in Patients With Advanced Liposarcoma or Other Advanced Solid Tumors
A Phase Ib/II Study of APG-115 in Combination With PD-1 Inhibitor in Patients With Advanced Liposarcoma or Other Advanced Solid Tumors
Who is this study for: Patients with advanced liposarcoma or other advanced solid tumors
Enrollment Status: Recruiting
Publish Date: February 26, 2025
Intervention Type: Drug
Study Drugs: APG-115, Toripalimab
Study Phase: Phase 1/Phase 2

Summary: Part 1 is a phase Ib standard 3 + 3 design, will be employed to determine the MTD of APG-115 by assessing the DLT of APG-115 in combination with PD-1 inhibitor(toripalimab) in advanced solid tumors. Part 2 is a Simon two-stage phase II study design. At RP2D of APG-115 in combination with toripalimab in advanced liposarcoma, approximately 34 patients will be treated with the combination until disea...

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