Multifocal Motor Neuropathy Overview

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Learn About Multifocal Motor Neuropathy

What is the definition of Multifocal Motor Neuropathy?
Multifocal motor neuropathy (MMN) causes damage to the nerves in the arms and legs. Nerve damage begins in adulthood and slowly gets worse over time. One side of the body may be more affected than the other. Symptoms of MMN may include weakness in the hands and lower arms; cramping; involuntary contractions or twitching; wrist drop or foot drop, and wasting of the affected muscles. MMN is thought to be due to an abnormal immune response, but the underlying cause is not clear. Diagnosis is based on the symptoms, clinical exam, and specific laboratory testing. Guidelines for diagnosis have been published.
What are the alternative names for Multifocal Motor Neuropathy?
  • Multifocal motor neuropathy
  • MMN
  • MMNCB
  • Multifocal motor neuropathy with conduction block
Who are the top Multifocal Motor Neuropathy Local Doctors?
Experienced in Multifocal Motor Neuropathy
Dr. Bela Ajtai
Neurology
Experienced in Multifocal Motor Neuropathy
Dr. Bela Ajtai
Neurology

Dent Neurologic Group Llp

3980 Sheridan Dr, 
Amherst, NY 
 (18.3 mi)
716-250-2000
Languages Spoken:
English
Offers Telehealth

Bela Ajtai is a Neurologist in Amherst, New York. Dr. Ajtai and is rated as an Experienced provider by MediFind in the treatment of Multifocal Motor Neuropathy. His top areas of expertise are Cerebellar Degeneration, Dementia, Cluster Headache, and Migraine.

Experienced in Multifocal Motor Neuropathy
Dr. Bennett H. Myers
Neurology
Experienced in Multifocal Motor Neuropathy
Dr. Bennett H. Myers
Neurology

Dent Neurologic Group Llp

3980 Sheridan Dr, 
Amherst, NY 
 (18.3 mi)
716-250-2000
Languages Spoken:
English
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Bennett Myers is a Neurologist in Amherst, New York. Dr. Myers and is rated as an Experienced provider by MediFind in the treatment of Multifocal Motor Neuropathy. His top areas of expertise are Multiple Sclerosis (MS), Hemangioblastoma, Relapsing Multiple Sclerosis (RMS), and Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's Disease).

 
 
 
 
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Experienced in Multifocal Motor Neuropathy
Carolina Barnett
Experienced in Multifocal Motor Neuropathy
Carolina Barnett
Toronto, ON, CA 
 (41.1 mi)

Carolina Barnett practices in Toronto, Canada. Barnett and is rated as an Experienced expert by MediFind in the treatment of Multifocal Motor Neuropathy. Her top areas of expertise are Myasthenia Gravis, Sensorimotor Polyneuropathy, Schwannomatosis, Chronic Inflammatory Demyelinating Polyneuropathy, and Thymectomy.

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What are the latest Multifocal Motor Neuropathy Clinical Trials?
A Phase 3, Randomized, Double-Blinded, Double-Dummy Study Evaluating the Efficacy and Safety of Empasiprubart Versus Intravenous Immunoglobulin in Adults with Multifocal Motor Neuropathy
A Phase 3, Randomized, Double-Blinded, Double-Dummy Study Evaluating the Efficacy and Safety of Empasiprubart Versus Intravenous Immunoglobulin in Adults with Multifocal Motor Neuropathy
Enrollment Status: Recruiting
Publish Date: February 19, 2025
Intervention Type: Biological, Other
Study Phase: Phase 3

Summary: The main purpose of this study is to compare empasiprubart and IVIg in adult patients with MMN. The study consists of a double-blinded part A (empasiprubart, IVIg) and an open-label part B (empasiprubart). The maximum study duration for participants is up to 49 months.

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A Phase 2, Randomized, Double-Blinded, Placebo-Controlled, Study to Evaluate Safety, Tolerability, Pharmacometrics, and Efficacy of DNTH103 in Adults with Multifocal Motor Neuropathy (MOMENTUM)
A Phase 2, Randomized, Double-Blinded, Placebo-Controlled, Study to Evaluate Safety, Tolerability, Pharmacometrics, and Efficacy of DNTH103 in Adults with Multifocal Motor Neuropathy (MOMENTUM)
Enrollment Status: Recruiting
Publish Date: January 30, 2025
Intervention Type: Drug
Study Phase: Phase 2

Summary: The purpose of this Phase 2 study is to evaluate the safety, tolerability, pharmacometrics, and efficacy of DNTH103 in participants with multifocal motor neuropathy (MMN).

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center