Piebaldism Overview
Learn About Piebaldism
Piebaldism is a condition characterized by the absence of cells called melanocytes in certain areas of the skin and hair. Melanocytes produce the pigment melanin, which contributes to hair, eye, and skin color. The absence of melanocytes leads to patches of skin and hair that are lighter than normal. Approximately 90 percent of affected individuals have a white section of hair near their front hairline (a white forelock). The eyelashes, the eyebrows, and the skin under the forelock may also be unpigmented.
Piebaldism can be caused by mutations in the KIT and SNAI2 genes. Piebaldism may also be a feature of other conditions, such as Waardenburg syndrome; these conditions have other genetic causes and additional signs and symptoms.
The prevalence of piebaldism is unknown.
This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder.
Christopher Ineama is a Physician Assistant in Fort Worth, Texas. Ineama and is rated as an Experienced provider by MediFind in the treatment of Piebaldism. His top area of expertise is Piebaldism.
Lenora Noroski is a Pediatric Allergy and Immunologist in Houston, Texas. Dr. Noroski and is rated as an Experienced provider by MediFind in the treatment of Piebaldism. Her top areas of expertise are Chronic Granulomatous Disease, Severe Combined Immunodeficiency (SCID), Infantile Neutropenia, and Piebaldism. Dr. Noroski is currently accepting new patients.
Texas Childrens Physician Group
Javier Chinen is a Pediatric Allergy and Immunologist and a Pediatrics provider in Houston, Texas. Dr. Chinen and is rated as an Experienced provider by MediFind in the treatment of Piebaldism. His top areas of expertise are Primary Immunodeficiency (PID), Secondary Immunodeficiency (SID), Hyper IGE Syndrome, Splenectomy, and Thymectomy. Dr. Chinen is currently accepting new patients.
Published Date: February 01, 2013
Published By: National Institutes of Health