Progressive Familial Intrahepatic Cholestasis Type 3 Overview

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Learn About Progressive Familial Intrahepatic Cholestasis Type 3

What is the definition of Progressive Familial Intrahepatic Cholestasis Type 3?
Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a rare condition that affects the liver. People with this condition generally develop signs and symptoms during late infancy or early childhood, which may include severe itching, jaundice, failure to thrive, portal hypertension (high blood pressure in the vein that provides blood to the liver) and hepatosplenomegaly (enlarged liver and spleen). The condition may progress to liver failure during childhood or adulthood. PFIC3 is caused by change in the ABCB4 gene and is inherited in an autosomal recessive manner.
What are the alternative names for Progressive Familial Intrahepatic Cholestasis Type 3?
  • Progressive familial intrahepatic cholestasis type 3
  • MDR3 deficiency
  • PFIC3
  • Progressive familial intrahepatic cholestasis with elevated serum gamma-glutamyltransferase
Who are the top Progressive Familial Intrahepatic Cholestasis Type 3 Local Doctors?
Advanced in Progressive Familial Intrahepatic Cholestasis Type 3
Dr. Karen Krok
Hepatology
Advanced in Progressive Familial Intrahepatic Cholestasis Type 3
Dr. Karen Krok
Hepatology

The Milton S Hershey Medical Center Physicians Group

500 University Dr, A410, 
Hershey, PA 
 (2.1 mi)
717-531-6261
Languages Spoken:
English
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Offers Telehealth

Karen Krok is a Hepatologist in Hershey, Pennsylvania. Dr. Krok and is rated as an Advanced provider by MediFind in the treatment of Progressive Familial Intrahepatic Cholestasis Type 3. Her top areas of expertise are Hepatitis, Nonalcoholic Steatohepatitis (NASH), Visceromegaly, Liver Transplant, and Endoscopy.

Experienced in Progressive Familial Intrahepatic Cholestasis Type 3
Dr. Kathryn L. Mcgillen
Radiology | Interventional Radiology
Experienced in Progressive Familial Intrahepatic Cholestasis Type 3
Dr. Kathryn L. Mcgillen
Radiology | Interventional Radiology

The Milton S Hershey Medical Center Physicians Group

500 University Dr, 
Hershey, PA 
 (2.1 mi)
717-531-8365
Experience:
17+ years
Languages Spoken:
English

Kathryn Mcgillen is a Radiologist and an Interventional Radiologist in Hershey, Pennsylvania. Dr. Mcgillen has been practicing medicine for over 17 years and is rated as an Experienced provider by MediFind in the treatment of Progressive Familial Intrahepatic Cholestasis Type 3. Her top areas of expertise are Visceromegaly, Progressive Familial Intrahepatic Cholestasis Type 3, Progressive Familial Intrahepatic Cholestasis Type 2, Progressive Familial Intrahepatic Cholestasis Type 1, and Lithotripsy.

 
 
 
 
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Experienced in Progressive Familial Intrahepatic Cholestasis Type 3
Dr. Ian Schreibman
Gastroenterology
Experienced in Progressive Familial Intrahepatic Cholestasis Type 3
Dr. Ian Schreibman
Gastroenterology

The Milton S Hershey Medical Center Physicians Group

500 University Dr, 
Hershey, PA 
 (2.1 mi)
717-531-8141
Languages Spoken:
English
See accepted insurances

Ian Schreibman is a Gastroenterologist in Hershey, Pennsylvania. Dr. Schreibman and is rated as an Experienced provider by MediFind in the treatment of Progressive Familial Intrahepatic Cholestasis Type 3. His top areas of expertise are Non-Alcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis (NASH), Hepatitis, Endoscopy, and Liver Transplant.

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Published Date: May 06, 2022
Published By: Genetic and Rare Diseases Informnation Center